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Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei.
Seufert F, Kuhn M, Hein M, Weiwad M, Vivoli M, Norville IH, Sarkar-Tyson M, Marshall LE, Schweimer K, Bruhn H, Rösch P, Harmer NJ, Sotriffer CA, Holzgrabe U. Seufert F, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5134-5147. doi: 10.1016/j.bmc.2016.08.025. Epub 2016 Aug 20. Bioorg Med Chem. 2016. PMID: 27591009
C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors.
Zlotos DP, Abdelmalek CM, Botros LS, Banoub MM, Mandour YM, Breitinger U, El Nady A, Breitinger HG, Sotriffer C, Villmann C, Jensen AA, Holzgrabe U. Zlotos DP, et al. Among authors: sotriffer c. J Nat Prod. 2021 Feb 26;84(2):382-394. doi: 10.1021/acs.jnatprod.0c01030. Epub 2021 Feb 17. J Nat Prod. 2021. PMID: 33596384
Glycolytic flux control by drugging phosphoglycolate phosphatase.
Jeanclos E, Schlötzer J, Hadamek K, Yuan-Chen N, Alwahsh M, Hollmann R, Fratz S, Yesilyurt-Gerhards D, Frankenbach T, Engelmann D, Keller A, Kaestner A, Schmitz W, Neuenschwander M, Hergenröder R, Sotriffer C, von Kries JP, Schindelin H, Gohla A. Jeanclos E, et al. Among authors: sotriffer c. Nat Commun. 2022 Nov 11;13(1):6845. doi: 10.1038/s41467-022-34228-2. Nat Commun. 2022. PMID: 36369173 Free PMC article.
Crystal structure of a covalently linked Aurora-A-MYCN complex.
Diebold M, Schönemann L, Eilers M, Sotriffer C, Schindelin H. Diebold M, et al. Among authors: sotriffer c. Acta Crystallogr D Struct Biol. 2023 Jan 1;79(Pt 1):1-9. doi: 10.1107/S2059798322011433. Epub 2023 Jan 1. Acta Crystallogr D Struct Biol. 2023. PMID: 36601802 Free PMC article.
107 results