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Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry.
Sottero B, Gamba P, Gargiulo S, Leonarduzzi G, Poli G. Sottero B, et al. Curr Med Chem. 2009;16(6):685-705. doi: 10.2174/092986709787458353. Curr Med Chem. 2009. PMID: 19199932 Review.
Up-regulation of the fibrogenic cytokine TGF-beta1 by oxysterols: a mechanistic link between cholesterol and atherosclerosis.
Leonarduzzi G, Sevanian A, Sottero B, Arkan MC, Biasi F, Chiarpotto E, Basaga H, Poli G. Leonarduzzi G, et al. Among authors: sottero b. FASEB J. 2001 Jul;15(9):1619-21. doi: 10.1096/fj.00-0668fje. FASEB J. 2001. PMID: 11427505 No abstract available.
Oxidized products of cholesterol: dietary and metabolic origin, and proatherosclerotic effects (review).
Leonarduzzi G, Sottero B, Poli G. Leonarduzzi G, et al. Among authors: sottero b. J Nutr Biochem. 2002 Dec;13(12):700-710. doi: 10.1016/s0955-2863(02)00222-x. J Nutr Biochem. 2002. PMID: 12550054
Oxysterol mixtures prevent proapoptotic effects of 7-ketocholesterol in macrophages: implications for proatherogenic gene modulation.
Biasi F, Leonarduzzi G, Vizio B, Zanetti D, Sevanian A, Sottero B, Verde V, Zingaro B, Chiarpotto E, Poli G. Biasi F, et al. Among authors: sottero b. FASEB J. 2004 Apr;18(6):693-5. doi: 10.1096/fj.03-0401fje. Epub 2004 Feb 20. FASEB J. 2004. PMID: 14977888
Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells.
Leonarduzzi G, Gamba P, Sottero B, Kadl A, Robbesyn F, Calogero RA, Biasi F, Chiarpotto E, Leitinger N, Sevanian A, Poli G. Leonarduzzi G, et al. Among authors: sottero b. Free Radic Biol Med. 2005 Nov 1;39(9):1152-61. doi: 10.1016/j.freeradbiomed.2005.06.024. Epub 2005 Aug 11. Free Radic Biol Med. 2005. PMID: 16214031
Expression and synthesis of TGFbeta1 is induced in macrophages by 9-oxononanoyl cholesterol, a major cholesteryl ester oxidation product.
Sottero B, Gamba P, Longhi M, Robbesyn F, Abuja PM, Schaur RJ, Poli G, Leonarduzzi G. Sottero B, et al. Biofactors. 2005;24(1-4):209-16. doi: 10.1002/biof.5520240125. Biofactors. 2005. PMID: 16403982
Early involvement of ROS overproduction in apoptosis induced by 7-ketocholesterol.
Leonarduzzi G, Vizio B, Sottero B, Verde V, Gamba P, Mascia C, Chiarpotto E, Poli G, Biasi F. Leonarduzzi G, et al. Among authors: sottero b. Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):375-80. doi: 10.1089/ars.2006.8.375. Antioxid Redox Signal. 2006. PMID: 16677084
Activation of the mitochondrial pathway of apoptosis by oxysterols.
Leonarduzzi G, Poli G, Sottero B, Biasi F. Leonarduzzi G, et al. Among authors: sottero b. Front Biosci. 2007 Jan 1;12:791-9. doi: 10.2741/2102. Front Biosci. 2007. PMID: 17127339 Review.
Lipid peroxidation and inflammatory molecules as markers of coronary artery disease.
Sottero B, Pozzi R, Leonarduzzi G, Aroasio E, Gamba P, Gargiulo S, Rabajoli F, Ferrari F, Greco Lucchina P, Poli G. Sottero B, et al. Redox Rep. 2007;12(1):81-5. doi: 10.1179/135100007X162275. Redox Rep. 2007. PMID: 17263916
Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture.
Leonarduzzi G, Gamba P, Gargiulo S, Sottero B, Kadl A, Biasi F, Chiarpotto E, Leitinger N, Vendemiale G, Serviddio G, Poli G. Leonarduzzi G, et al. Among authors: sottero b. Aging Cell. 2008 Jun;7(3):375-82. doi: 10.1111/j.1474-9726.2008.00386.x. Epub 2008 Mar 10. Aging Cell. 2008. PMID: 18331615
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