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Measuring single cell divisions in human tissues from multi-region sequencing data.
Werner B, Case J, Williams MJ, Chkhaidze K, Temko D, Fernández-Mateos J, Cresswell GD, Nichol D, Cross W, Spiteri I, Huang W, Tomlinson IPM, Barnes CP, Graham TA, Sottoriva A. Werner B, et al. Among authors: sottoriva a. Nat Commun. 2020 Feb 25;11(1):1035. doi: 10.1038/s41467-020-14844-6. Nat Commun. 2020. PMID: 32098957 Free PMC article.
Epigenetic profile of human adventitial progenitor cells correlates with therapeutic outcomes in a mouse model of limb ischemia.
Gubernator M, Slater SC, Spencer HL, Spiteri I, Sottoriva A, Riu F, Rowlinson J, Avolio E, Katare R, Mangialardi G, Oikawa A, Reni C, Campagnolo P, Spinetti G, Touloumis A, Tavaré S, Prandi F, Pesce M, Hofner M, Klemens V, Emanueli C, Angelini G, Madeddu P. Gubernator M, et al. Among authors: sottoriva a. Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):675-88. doi: 10.1161/ATVBAHA.114.304989. Epub 2015 Jan 8. Arterioscler Thromb Vasc Biol. 2015. PMID: 25573856
A Big Bang model of human colorectal tumor growth.
Sottoriva A, Kang H, Ma Z, Graham TA, Salomon MP, Zhao J, Marjoram P, Siegmund K, Press MF, Shibata D, Curtis C. Sottoriva A, et al. Nat Genet. 2015 Mar;47(3):209-16. doi: 10.1038/ng.3214. Epub 2015 Feb 9. Nat Genet. 2015. PMID: 25665006 Free PMC article.
Identification of neutral tumor evolution across cancer types.
Williams MJ, Werner B, Barnes CP, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: sottoriva a. Nat Genet. 2016 Mar;48(3):238-244. doi: 10.1038/ng.3489. Epub 2016 Jan 18. Nat Genet. 2016. PMID: 26780609 Free PMC article.
Functional versus non-functional intratumor heterogeneity in cancer.
Williams MJ, Werner B, Graham TA, Sottoriva A. Williams MJ, et al. Among authors: sottoriva a. Mol Cell Oncol. 2016 Apr 22;3(4):e1162897. doi: 10.1080/23723556.2016.1162897. eCollection 2016 Jul. Mol Cell Oncol. 2016. PMID: 27652316 Free PMC article.
Measuring cancer evolution from the genome.
Graham TA, Sottoriva A. Graham TA, et al. Among authors: sottoriva a. J Pathol. 2017 Jan;241(2):183-191. doi: 10.1002/path.4821. Epub 2016 Nov 18. J Pathol. 2017. PMID: 27741350 Review.
71 results