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Cytotoxicity of cyclophosphamide, paclitaxel, and docetaxel for tumor cell lines in vitro: effects of concentration, time and cytochrome P450-catalyzed metabolism.
Gut I, Danielová V, Holubová J, Soucek P, Klucková H. Gut I, et al. Among authors: soucek p. Arch Toxicol. 2000 Oct;74(8):437-46. doi: 10.1007/s002040000141. Arch Toxicol. 2000. PMID: 11097380
Cytochrome P450 destruction and radical scavenging by benzene and its metabolites. Evidence for the key role of quinones.
Soucek P, Filipcova B, Gut I. Soucek P, et al. Biochem Pharmacol. 1994 Jun 15;47(12):2233-42. doi: 10.1016/0006-2952(94)90261-5. Biochem Pharmacol. 1994. PMID: 8031317
Exposure to various benzene derivatives differently induces cytochromes P450 2B1 and P450 2E1 in rat liver.
Gut I, Terelius Y, Frantík E, Linhart I, Soucek P, Filipcová B, Klucková H. Gut I, et al. Among authors: soucek p. Arch Toxicol. 1993;67(4):237-43. doi: 10.1007/BF01974342. Arch Toxicol. 1993. PMID: 8517779
Identification of the highly polymorphic S-mephenytoin hydroxylase in humans.
Soucek P, Guo Z, Sandhu P, Martin MV, Cosme J, Beaune PH, Guengerich FP. Soucek P, et al. Arch Toxicol Suppl. 1996;18:437. doi: 10.1007/978-3-642-61105-6_40. Arch Toxicol Suppl. 1996. PMID: 8678819 No abstract available.
The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives.
Gut I, Nedelcheva V, Soucek P, Stopka P, Vodicka P, Gelboin HV, Ingelman-Sundberg M. Gut I, et al. Among authors: soucek p. Arch Toxicol. 1996;71(1-2):45-56. doi: 10.1007/s002040050357. Arch Toxicol. 1996. PMID: 9010585
Cytochromes P450 in benzene metabolism and involvement of their metabolites and reactive oxygen species in toxicity.
Gut I, Nedelcheva V, Soucek P, Stopka P, Tichavská B. Gut I, et al. Among authors: soucek p. Environ Health Perspect. 1996 Dec;104 Suppl 6(Suppl 6):1211-8. doi: 10.1289/ehp.961041211. Environ Health Perspect. 1996. PMID: 9118895 Free PMC article.
Cytochrome P450 catalyzed oxidation of monochlorobenzene, 1,2- and 1,4-dichlorobenzene in rat, mouse, and human liver microsomes.
Nedelcheva V, Gut I, Soucek P, Frantík E. Nedelcheva V, et al. Among authors: soucek p. Chem Biol Interact. 1998 Aug 14;115(1):53-70. doi: 10.1016/s0009-2797(98)00058-1. Chem Biol Interact. 1998. PMID: 9817075
Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression.
Nedelcheva V, Gut I, Soucek P, Tichavská B, Týnkova L, Mráz J, Guengerich FP, Ingelman-Sundberg M. Nedelcheva V, et al. Among authors: soucek p. Arch Toxicol. 1999 Feb;73(1):33-40. doi: 10.1007/s002040050583. Arch Toxicol. 1999. PMID: 10207612
Cytochrome P450 destruction by quinones: comparison of effects in rat and human liver microsomes.
Soucek P. Soucek P. Chem Biol Interact. 1999 Aug 1;121(3):223-36. doi: 10.1016/s0009-2797(99)00100-3. Chem Biol Interact. 1999. PMID: 10462055
Expression of cytochrome P450 2A6 in Escherichia coli: purification, spectral and catalytic characterization, and preparation of polyclonal antibodies.
Soucek P. Soucek P. Arch Biochem Biophys. 1999 Oct 15;370(2):190-200. doi: 10.1006/abbi.1999.1388. Arch Biochem Biophys. 1999. PMID: 10510277
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