Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products.
Long S, Resende DISP, Kijjoa A, Silva AMS, Pina A, Fernández-Marcelo T, Vasconcelos MH, Sousa E, Pinto MMM.
Long S, et al.
Mar Drugs. 2018 Jul 31;16(8):261. doi: 10.3390/md16080261.
Mar Drugs. 2018.
PMID: 30065225
Free PMC article.
The marine natural product fiscalin B (4c), and antienantiomers (4b, 5b, and 5c) were synthesized via a one-pot approach, while the syn enantiomers (4a, 4d, 5a, and 5d) were synthetized by a multi-step procedure. These strategies used anthranilic acid (i), chiral N-protect …
The marine natural product fiscalin B (4c), and antienantiomers (4b, 5b, and 5c) were synthesized via a one-pot approach, while the syn enan …