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ABM-1 and ABM-2 homology sequences: consensus docking sites for actin-based motility defined by oligoproline regions in Listeria ActA surface protein and human VASP.
Purich DL, Southwick FS. Purich DL, et al. Among authors: southwick fs. Biochem Biophys Res Commun. 1997 Feb 24;231(3):686-91. doi: 10.1006/bbrc.1997.6158. Biochem Biophys Res Commun. 1997. PMID: 9070872
Phosphoinositide 3-kinase is required for intracellular Listeria monocytogenes actin-based motility and filopod formation.
Sidhu G, Li W, Laryngakis N, Bishai E, Balla T, Southwick F. Sidhu G, et al. Among authors: southwick f. J Biol Chem. 2005 Mar 25;280(12):11379-86. doi: 10.1074/jbc.M414533200. Epub 2005 Jan 10. J Biol Chem. 2005. PMID: 15642729
Gelsolin mediates calcium-dependent disassembly of Listeria actin tails.
Larson L, Arnaudeau S, Gibson B, Li W, Krause R, Hao B, Bamburg JR, Lew DP, Demaurex N, Southwick F. Larson L, et al. Among authors: southwick f. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1921-6. doi: 10.1073/pnas.0409062102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671163 Free PMC article.
A CapG gain-of-function mutant reveals critical structural and functional determinants for actin filament severing.
Zhang Y, Vorobiev SM, Gibson BG, Hao B, Sidhu GS, Mishra VS, Yarmola EG, Bubb MR, Almo SC, Southwick FS. Zhang Y, et al. Among authors: southwick fs. EMBO J. 2006 Oct 4;25(19):4458-67. doi: 10.1038/sj.emboj.7601323. Epub 2006 Sep 14. EMBO J. 2006. PMID: 16977317 Free PMC article.
Bacillus anthracis edema toxin impairs neutrophil actin-based motility.
Szarowicz SE, During RL, Li W, Quinn CP, Tang WJ, Southwick FS. Szarowicz SE, et al. Among authors: southwick fs. Infect Immun. 2009 Jun;77(6):2455-64. doi: 10.1128/IAI.00839-08. Epub 2009 Apr 6. Infect Immun. 2009. PMID: 19349425 Free PMC article.
Southwick, J. Infect. Dis. 192:837-845, 2005), and we now find that LT combined with ET causes an additive inhibition of PMN chemokinesis, polarization, chemotaxis, and FMLP (N-formyl-met-leu-phe)-induced actin assembly. ...
Southwick, J. Infect. Dis. 192:837-845, 2005), and we now find that LT combined with ET causes an additive inhibition of PMN chemokin
Anthrax lethal toxin paralyzes actin-based motility by blocking Hsp27 phosphorylation.
During RL, Gibson BG, Li W, Bishai EA, Sidhu GS, Landry J, Southwick FS. During RL, et al. Among authors: southwick fs. EMBO J. 2007 May 2;26(9):2240-50. doi: 10.1038/sj.emboj.7601687. Epub 2007 Apr 19. EMBO J. 2007. PMID: 17446863 Free PMC article.
Anthrax lethal toxin paralyzes neutrophil actin-based motility.
During RL, Li W, Hao B, Koenig JM, Stephens DS, Quinn CP, Southwick FS. During RL, et al. Among authors: southwick fs. J Infect Dis. 2005 Sep 1;192(5):837-45. doi: 10.1086/432516. Epub 2005 Jul 21. J Infect Dis. 2005. PMID: 16088833
CapG(-/-) mice have specific host defense defects that render them more susceptible than CapG(+/+) mice to Listeria monocytogenes infection but not to Salmonella enterica serovar Typhimurium infection.
Parikh SS, Litherland SA, Clare-Salzler MJ, Li W, Gulig PA, Southwick FS. Parikh SS, et al. Among authors: southwick fs. Infect Immun. 2003 Nov;71(11):6582-90. doi: 10.1128/iai.71.11.6582-6590.2003. Infect Immun. 2003. PMID: 14573680 Free PMC article.
Depolymerization of actin filaments by profilin. Effects of profilin on capping protein function.
Bubb MR, Yarmola EG, Gibson BG, Southwick FS. Bubb MR, et al. Among authors: southwick fs. J Biol Chem. 2003 Jul 4;278(27):24629-35. doi: 10.1074/jbc.M302796200. Epub 2003 May 2. J Biol Chem. 2003. PMID: 12730212
Actin-based endosome and phagosome rocketing in macrophages: activation by the secretagogue antagonists lanthanum and zinc.
Southwick FS, Li W, Zhang F, Zeile WL, Purich DL. Southwick FS, et al. Cell Motil Cytoskeleton. 2003 Jan;54(1):41-55. doi: 10.1002/cm.10083. Cell Motil Cytoskeleton. 2003. PMID: 12451594
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