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Page 1
2-Aminoadipic acid is a biomarker for diabetes risk.
Wang TJ, Ngo D, Psychogios N, Dejam A, Larson MG, Vasan RS, Ghorbani A, O'Sullivan J, Cheng S, Rhee EP, Sinha S, McCabe E, Fox CS, O'Donnell CJ, Ho JE, Florez JC, Magnusson M, Pierce KA, Souza AL, Yu Y, Carter C, Light PE, Melander O, Clish CB, Gerszten RE. Wang TJ, et al. Among authors: souza al. J Clin Invest. 2013 Oct;123(10):4309-17. doi: 10.1172/JCI64801. Epub 2013 Sep 16. J Clin Invest. 2013. PMID: 24091325 Free PMC article.
Metabolite profiles and the risk of developing diabetes.
Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE. Wang TJ, et al. Nat Med. 2011 Apr;17(4):448-53. doi: 10.1038/nm.2307. Epub 2011 Mar 20. Nat Med. 2011. PMID: 21423183 Free PMC article.
Metabolite profiling identifies pathways associated with metabolic risk in humans.
Cheng S, Rhee EP, Larson MG, Lewis GD, McCabe EL, Shen D, Palma MJ, Roberts LD, Dejam A, Souza AL, Deik AA, Magnusson M, Fox CS, O'Donnell CJ, Vasan RS, Melander O, Clish CB, Gerszten RE, Wang TJ. Cheng S, et al. Among authors: souza al. Circulation. 2012 May 8;125(18):2222-31. doi: 10.1161/CIRCULATIONAHA.111.067827. Epub 2012 Apr 11. Circulation. 2012. PMID: 22496159 Free PMC article.
A combined epidemiologic and metabolomic approach improves CKD prediction.
Rhee EP, Clish CB, Ghorbani A, Larson MG, Elmariah S, McCabe E, Yang Q, Cheng S, Pierce K, Deik A, Souza AL, Farrell L, Domos C, Yeh RW, Palacios I, Rosenfield K, Vasan RS, Florez JC, Wang TJ, Fox CS, Gerszten RE. Rhee EP, et al. Among authors: souza al. J Am Soc Nephrol. 2013 Jul;24(8):1330-8. doi: 10.1681/ASN.2012101006. Epub 2013 May 16. J Am Soc Nephrol. 2013. PMID: 23687356 Free PMC article.
Distinct metabolomic signatures are associated with longevity in humans.
Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Cheng S, et al. Among authors: souza al. Nat Commun. 2015 Apr 13;6:6791. doi: 10.1038/ncomms7791. Nat Commun. 2015. PMID: 25864806 Free PMC article.
A genome-wide association study of the human metabolome in a community-based cohort.
Rhee EP, Ho JE, Chen MH, Shen D, Cheng S, Larson MG, Ghorbani A, Shi X, Helenius IT, O'Donnell CJ, Souza AL, Deik A, Pierce KA, Bullock K, Walford GA, Vasan RS, Florez JC, Clish C, Yeh JR, Wang TJ, Gerszten RE. Rhee EP, et al. Among authors: souza al. Cell Metab. 2013 Jul 2;18(1):130-43. doi: 10.1016/j.cmet.2013.06.013. Cell Metab. 2013. PMID: 23823483 Free PMC article.
Targeted metabolomics.
Roberts LD, Souza AL, Gerszten RE, Clish CB. Roberts LD, et al. Among authors: souza al. Curr Protoc Mol Biol. 2012 Apr;Chapter 30:Unit 30.2.1-24. doi: 10.1002/0471142727.mb3002s98. Curr Protoc Mol Biol. 2012. PMID: 22470063 Free PMC article.
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.
Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. Roberts LD, et al. Among authors: souza al. Cell Metab. 2014 Jan 7;19(1):96-108. doi: 10.1016/j.cmet.2013.12.003. Cell Metab. 2014. PMID: 24411942 Free PMC article. Clinical Trial.
Metabolic signatures of exercise in human plasma.
Lewis GD, Farrell L, Wood MJ, Martinovic M, Arany Z, Rowe GC, Souza A, Cheng S, McCabe EL, Yang E, Shi X, Deo R, Roth FP, Asnani A, Rhee EP, Systrom DM, Semigran MJ, Vasan RS, Carr SA, Wang TJ, Sabatine MS, Clish CB, Gerszten RE. Lewis GD, et al. Sci Transl Med. 2010 May 26;2(33):33ra37. doi: 10.1126/scitranslmed.3001006. Sci Transl Med. 2010. PMID: 20505214 Free PMC article.
379 results