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Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells.
Gao Y, Souza-Fonseca-Guimaraes F, Bald T, Ng SS, Young A, Ngiow SF, Rautela J, Straube J, Waddell N, Blake SJ, Yan J, Bartholin L, Lee JS, Vivier E, Takeda K, Messaoudene M, Zitvogel L, Teng MWL, Belz GT, Engwerda CR, Huntington ND, Nakamura K, Hölzel M, Smyth MJ. Gao Y, et al. Nat Immunol. 2017 Sep;18(9):1004-1015. doi: 10.1038/ni.3800. Epub 2017 Jul 31. Nat Immunol. 2017. PMID: 28759001
Myeloid TGF-β responsiveness promotes metastases.
Souza-Fonseca-Guimaraes F, Smyth MJ. Souza-Fonseca-Guimaraes F, et al. Cancer Discov. 2013 Aug;3(8):846-8. doi: 10.1158/2159-8290.CD-13-0271. Cancer Discov. 2013. PMID: 23928773
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells.
Sathe P, Delconte RB, Souza-Fonseca-Guimaraes F, Seillet C, Chopin M, Vandenberg CJ, Rankin LC, Mielke LA, Vikstrom I, Kolesnik TB, Nicholson SE, Vivier E, Smyth MJ, Nutt SL, Glaser SP, Strasser A, Belz GT, Carotta S, Huntington ND. Sathe P, et al. Nat Commun. 2014 Aug 14;5:4539. doi: 10.1038/ncomms5539. Nat Commun. 2014. PMID: 25119382 Free article.
CD3bright signals on γδ T cells identify IL-17A-producing Vγ6Vδ1+ T cells.
Paget C, Chow MT, Gherardin NA, Beavis PA, Uldrich AP, Duret H, Hassane M, Souza-Fonseca-Guimaraes F, Mogilenko DA, Staumont-Sallé D, Escalante NK, Hill GR, Neeson P, Ritchie DS, Dombrowicz D, Mallevaey T, Trottein F, Belz GT, Godfrey DI, Smyth MJ. Paget C, et al. Immunol Cell Biol. 2015 Feb;93(2):198-212. doi: 10.1038/icb.2014.94. Epub 2014 Nov 11. Immunol Cell Biol. 2015. PMID: 25385067 Free article.
DNAM-1 expression marks an alternative program of NK cell maturation.
Martinet L, Ferrari De Andrade L, Guillerey C, Lee JS, Liu J, Souza-Fonseca-Guimaraes F, Hutchinson DS, Kolesnik TB, Nicholson SE, Huntington ND, Smyth MJ. Martinet L, et al. Cell Rep. 2015 Apr 7;11(1):85-97. doi: 10.1016/j.celrep.2015.03.006. Epub 2015 Mar 26. Cell Rep. 2015. PMID: 25818301 Free article.
NK cells require IL-28R for optimal in vivo activity.
Souza-Fonseca-Guimaraes F, Young A, Mittal D, Martinet L, Bruedigam C, Takeda K, Andoniou CE, Degli-Esposti MA, Hill GR, Smyth MJ. Souza-Fonseca-Guimaraes F, et al. Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2376-84. doi: 10.1073/pnas.1424241112. Epub 2015 Apr 21. Proc Natl Acad Sci U S A. 2015. PMID: 25901316 Free PMC article.
IFN type III: in vivo NK cell response.
Souza-Fonseca-Guimaraes F, Young A, Smyth MJ. Souza-Fonseca-Guimaraes F, et al. Oncotarget. 2015 Aug 21;6(24):19960-1. doi: 10.18632/oncotarget.4758. Oncotarget. 2015. PMID: 26343521 Free PMC article. No abstract available.
87 results