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Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates.
Humbert O, Radtke S, Samuelson C, Carrillo RR, Perez AM, Reddy SS, Lux C, Pattabhi S, Schefter LE, Negre O, Lee CM, Bao G, Adair JE, Peterson CW, Rawlings DJ, Scharenberg AM, Kiem HP. Humbert O, et al. Among authors: pattabhi s. Sci Transl Med. 2019 Jul 31;11(503):eaaw3768. doi: 10.1126/scitranslmed.aaw3768. Sci Transl Med. 2019. PMID: 31366580 Free PMC article.
TALEN-Mediated Gene Editing of HBG in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction.
Lux CT, Pattabhi S, Berger M, Nourigat C, Flowers DA, Negre O, Humbert O, Yang JG, Lee C, Jacoby K, Bernstein I, Kiem HP, Scharenberg A, Rawlings DJ. Lux CT, et al. Among authors: pattabhi s. Mol Ther Methods Clin Dev. 2018 Dec 31;12:175-183. doi: 10.1016/j.omtm.2018.12.008. eCollection 2019 Mar 15. Mol Ther Methods Clin Dev. 2018. PMID: 30705922 Free PMC article.
Applying TLR synergy in immunotherapy: implications in cutaneous leishmaniasis.
Raman VS, Bhatia A, Picone A, Whittle J, Bailor HR, O'Donnell J, Pattabhi S, Guderian JA, Mohamath R, Duthie MS, Reed SG. Raman VS, et al. Among authors: pattabhi s. J Immunol. 2010 Aug 1;185(3):1701-10. doi: 10.4049/jimmunol.1000238. Epub 2010 Jul 2. J Immunol. 2010. PMID: 20601594 Free PMC article.
14 results