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Immunology of hepatitis C virus infections.
Spaan M, Janssen HL, Boonstra A. Spaan M, et al. Best Pract Res Clin Gastroenterol. 2012 Aug;26(4):391-400. doi: 10.1016/j.bpg.2012.09.005. Best Pract Res Clin Gastroenterol. 2012. PMID: 23199499 Review.
Erythropoietin administration suppresses human monocyte function in vitro and during therapy-induced anemia in HCV patients.
Spaan M, Groothuismink ZM, Koning L, Roomer R, Janssen HL, De Knegt RJ, Boonstra A. Spaan M, et al. Antiviral Res. 2013 Jun;98(3):469-75. doi: 10.1016/j.antiviral.2013.04.003. Epub 2013 Apr 11. Antiviral Res. 2013. PMID: 23583759
CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses.
Spaan M, Kreefft K, de Graav GN, Brouwer WP, de Knegt RJ, ten Kate FJ, Baan CC, Vanwolleghem T, Janssen HL, Boonstra A. Spaan M, et al. J Hepatol. 2015 Feb;62(2):303-10. doi: 10.1016/j.jhep.2014.09.024. Epub 2014 Oct 2. J Hepatol. 2015. PMID: 25281860
Immunological Analysis During Interferon-Free Therapy for Chronic Hepatitis C Virus Infection Reveals Modulation of the Natural Killer Cell Compartment.
Spaan M, van Oord G, Kreefft K, Hou J, Hansen BE, Janssen HL, de Knegt RJ, Boonstra A. Spaan M, et al. J Infect Dis. 2016 Jan 15;213(2):216-23. doi: 10.1093/infdis/jiv391. Epub 2015 Jul 28. J Infect Dis. 2016. PMID: 26223768 Clinical Trial.
Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy.
Spaan M, Hullegie SJ, Beudeker BJ, Kreefft K, van Oord GW, Groothuismink ZM, van Tilborg M, Rijnders B, de Knegt RJ, Claassen MA, Boonstra A. Spaan M, et al. PLoS One. 2016 Jul 14;11(7):e0159243. doi: 10.1371/journal.pone.0159243. eCollection 2016. PLoS One. 2016. PMID: 27416100 Free PMC article.
Hepatitis delta genotype 5 is associated with favourable disease outcome and better response to treatment compared to genotype 1.
Spaan M, Carey I, Bruce M, Shang D, Horner M, Dusheiko G, Agarwal K. Spaan M, et al. J Hepatol. 2020 Jun;72(6):1097-1104. doi: 10.1016/j.jhep.2019.12.028. Epub 2020 Jan 22. J Hepatol. 2020. PMID: 31981726
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