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Soma to germline inheritance of extrachromosomal genetic information via a LINE-1 reverse transcriptase-based mechanism.
Spadafora C. Spadafora C. Bioessays. 2016 Aug;38(8):726-33. doi: 10.1002/bies.201500197. Epub 2016 Jun 17. Bioessays. 2016. PMID: 27315018 Review.
Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells.
Briggs EM, Ha S, Mita P, Brittingham G, Sciamanna I, Spadafora C, Logan SK. Briggs EM, et al. Among authors: spadafora c. Mob DNA. 2018 Jan 3;9:1. doi: 10.1186/s13100-017-0106-z. eCollection 2018. Mob DNA. 2018. PMID: 29308092 Free PMC article.
The "evolutionary field" hypothesis. Non-Mendelian transgenerational inheritance mediates diversification and evolution.
Spadafora C. Spadafora C. Prog Biophys Mol Biol. 2018 May;134:27-37. doi: 10.1016/j.pbiomolbio.2017.12.001. Epub 2017 Dec 6. Prog Biophys Mol Biol. 2018. PMID: 29223657 Review.
Sperm-Mediated Transgenerational Inheritance.
Spadafora C. Spadafora C. Front Microbiol. 2017 Dec 4;8:2401. doi: 10.3389/fmicb.2017.02401. eCollection 2017. Front Microbiol. 2017. PMID: 29255455 Free PMC article.
LINE-1 retrotransposon copies are amplified during murine early embryo development.
Vitullo P, Sciamanna I, Baiocchi M, Sinibaldi-Vallebona P, Spadafora C. Vitullo P, et al. Among authors: spadafora c. Mol Reprod Dev. 2012 Feb;79(2):118-27. doi: 10.1002/mrd.22003. Epub 2011 Dec 2. Mol Reprod Dev. 2012. PMID: 22139884
Generation of biologically active retro-genes upon interaction of mouse spermatozoa with exogenous DNA.
Pittoggi C, Beraldi R, Sciamanna I, Barberi L, Giordano R, Magnano AR, Torosantucci L, Pescarmona E, Spadafora C. Pittoggi C, et al. Among authors: spadafora c. Mol Reprod Dev. 2006 Oct;73(10):1239-46. doi: 10.1002/mrd.20550. Mol Reprod Dev. 2006. PMID: 16850445
Soma-to-germline transmission of RNA in mice xenografted with human tumour cells: possible transport by exosomes.
Cossetti C, Lugini L, Astrologo L, Saggio I, Fais S, Spadafora C. Cossetti C, et al. Among authors: spadafora c. PLoS One. 2014 Jul 3;9(7):e101629. doi: 10.1371/journal.pone.0101629. eCollection 2014. PLoS One. 2014. PMID: 24992257 Free PMC article.
A LINE-1-encoded reverse transcriptase-dependent regulatory mechanism is active in embryogenesis and tumorigenesis.
Spadafora C. Spadafora C. Ann N Y Acad Sci. 2015 Apr;1341:164-71. doi: 10.1111/nyas.12637. Epub 2015 Jan 13. Ann N Y Acad Sci. 2015. PMID: 25586649
Enhanced expression of LINE-1-encoded ORF2 protein in early stages of colon and prostate transformation.
De Luca C, Guadagni F, Sinibaldi-Vallebona P, Sentinelli S, Gallucci M, Hoffmann A, Schumann GG, Spadafora C, Sciamanna I. De Luca C, et al. Among authors: spadafora c. Oncotarget. 2016 Jan 26;7(4):4048-61. doi: 10.18632/oncotarget.6767. Oncotarget. 2016. PMID: 26716650 Free PMC article.
Sperm-mediated gene transfer: applications and implications.
Smith K, Spadafora C. Smith K, et al. Among authors: spadafora c. Bioessays. 2005 May;27(5):551-62. doi: 10.1002/bies.20211. Bioessays. 2005. PMID: 15832378
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