Spain L - Search Results

1

Management of toxicities of immune checkpoint inhibitors.

Spain L, Diem S, Larkin J. Spain L, et al. Cancer Treat Rev. 2016 Mar;44:51-60. doi: 10.1016/j.ctrv.2016.02.001. Epub 2016 Feb 6. Cancer Treat Rev. 2016. PMID: 26874776 Review.

2

Pervasive chromosomal instability and karyotype order in tumour evolution.

Watkins TBK, Lim EL, Petkovic M, Elizalde S, Birkbak NJ, Wilson GA, Moore DA, Grönroos E, Rowan A, Dewhurst SM, Demeulemeester J, Dentro SC, Horswell S, Au L, Haase K, Escudero M, Rosenthal R, Bakir MA, Xu H, Litchfield K, Lu WT, Mourikis TP, Dietzen M, Spain L, Cresswell GD, Biswas D, Lamy P, Nordentoft I, Harbst K, Castro-Giner F, Yates LR, Caramia F, Jaulin F, Vicier C, Tomlinson IPM, Brastianos PK, Cho RJ, Bastian BC, Dyrskjøt L, Jönsson GB, Savas P, Loi S, Campbell PJ, Andre F, Luscombe NM, Steeghs N, Tjan-Heijnen VCG, Szallasi Z, Turajlic S, Jamal-Hanjani M, Van Loo P, Bakhoum SF, Schwarz RF, McGranahan N, Swanton C. Watkins TBK, et al. Among authors: spain l. Nature. 2020 Nov;587(7832):126-132. doi: 10.1038/s41586-020-2698-6. Epub 2020 Sep 2. Nature. 2020. PMID: 32879494 Free PMC article.

3

Combination immune checkpoint blockade with ipilimumab and nivolumab in the management of advanced melanoma.

Spain L, Larkin J. Spain L, et al. Expert Opin Biol Ther. 2016;16(3):389-96. doi: 10.1517/14712598.2016.1141195. Epub 2016 Feb 1. Expert Opin Biol Ther. 2016. PMID: 26750801 Review.

4

Serum lactate dehydrogenase as an early marker for outcome in patients treated with anti-PD-1 therapy in metastatic melanoma.

Diem S, Kasenda B, Spain L, Martin-Liberal J, Marconcini R, Gore M, Larkin J. Diem S, et al. Among authors: spain l. Br J Cancer. 2016 Feb 2;114(3):256-61. doi: 10.1038/bjc.2015.467. Epub 2016 Jan 21. Br J Cancer. 2016. PMID: 26794281 Free PMC article.

5

Acute renal allograft rejection after immune checkpoint inhibitor therapy for metastatic melanoma.

Spain L, Higgins R, Gopalakrishnan K, Turajlic S, Gore M, Larkin J. Spain L, et al. Ann Oncol. 2016 Jun;27(6):1135-1137. doi: 10.1093/annonc/mdw130. Epub 2016 Mar 6. Ann Oncol. 2016. PMID: 26951628 Free article.

6

Combination dabrafenib and trametinib in the management of advanced melanoma with BRAFV600 mutations.

Spain L, Julve M, Larkin J. Spain L, et al. Expert Opin Pharmacother. 2016;17(7):1031-8. doi: 10.1517/14656566.2016.1168805. Epub 2016 Apr 12. Expert Opin Pharmacother. 2016. PMID: 27027150 Review.

7

Determining predictive factors for immune checkpoint inhibitor toxicity: Response to Letter to the Editors "A case report of insulin-dependent diabetes as immune-related toxicity of pembrolizumab: presentation, management and outcome".

Spain L, Larkin J, Martin-Liberal J. Spain L, et al. Cancer Immunol Immunother. 2016 Jun;65(6):769-70. doi: 10.1007/s00262-016-1845-2. Epub 2016 May 19. Cancer Immunol Immunother. 2016. PMID: 27194054 No abstract available.

8

Weighing up the pros and cons of immune checkpoint inhibitors in the treatment of melanoma.

Spain L, Larkin J. Spain L, et al. Immunotherapy. 2016 Jun;8(6):677-9. doi: 10.2217/imt.16.6. Immunotherapy. 2016. PMID: 27197536 Free article. No abstract available.

9

Efficacy and toxicity of rechallenge with combination immune checkpoint blockade in metastatic melanoma: a case series.

Spain L, Walls G, Messiou C, Turajlic S, Gore M, Larkin J. Spain L, et al. Cancer Immunol Immunother. 2017 Jan;66(1):113-117. doi: 10.1007/s00262-016-1926-2. Epub 2016 Nov 12. Cancer Immunol Immunother. 2017. PMID: 27838762

10

Thyroid abnormalities following the use of cytotoxic T-lymphocyte antigen-4 and programmed death receptor protein-1 inhibitors in the treatment of melanoma.

Morganstein DL, Lai Z, Spain L, Diem S, Levine D, Mace C, Gore M, Larkin J. Morganstein DL, et al. Among authors: spain l. Clin Endocrinol (Oxf). 2017 Apr;86(4):614-620. doi: 10.1111/cen.13297. Epub 2017 Jan 27. Clin Endocrinol (Oxf). 2017. PMID: 28028828

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