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Modelling cancer progression using Mutual Hazard Networks.
Schill R, Solbrig S, Wettig T, Spang R. Schill R, et al. Among authors: spang r. Bioinformatics. 2020 Jan 1;36(1):241-249. doi: 10.1093/bioinformatics/btz513. Bioinformatics. 2020. PMID: 31250881 Free PMC article.
Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models.
Pirkl M, Hand E, Kube D, Spang R. Pirkl M, et al. Among authors: spang r. Bioinformatics. 2016 Mar 15;32(6):893-900. doi: 10.1093/bioinformatics/btv680. Epub 2015 Nov 17. Bioinformatics. 2016. PMID: 26581413 Free PMC article.
Using B-NEM we then resolve BCR signalling via PI3K and TAK1 kinases in BL2 lymphoma cell lines. AVAILABILITY AND IMPLEMENTATION: R code is available at https://github.com/MartinFXP/B-NEM (github). The BCR signalling dataset is available at the GEO database (http://www.ncb …
Using B-NEM we then resolve BCR signalling via PI3K and TAK1 kinases in BL2 lymphoma cell lines. AVAILABILITY AND IMPLEMENTATION: R c …
Inferring cellular networks--a review.
Markowetz F, Spang R. Markowetz F, et al. Among authors: spang r. BMC Bioinformatics. 2007 Sep 27;8 Suppl 6(Suppl 6):S5. doi: 10.1186/1471-2105-8-S6-S5. BMC Bioinformatics. 2007. PMID: 17903286 Free PMC article. Review.
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