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143 results
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Computational diagnostics with gene expression profiles.
Lottaz C, Kostka D, Markowetz F, Spang R. Lottaz C, et al. Among authors: spang r. Methods Mol Biol. 2008;453:281-96. doi: 10.1007/978-1-60327-429-6_15. Methods Mol Biol. 2008. PMID: 18712310
Gene expression profiling reveals a close relationship between follicular lymphoma grade 3A and 3B, but distinct profiles of follicular lymphoma grade 1 and 2.
Horn H, Kohler C, Witzig R, Kreuz M, Leich E, Klapper W, Hummel M, Loeffler M, Trümper L, Spang R, Rosenwald A, Ott G; Molecular Mechanisms in Malignant Lymphomas (MMML) Network Project. Horn H, et al. Among authors: spang r. Haematologica. 2018 Jul;103(7):1182-1190. doi: 10.3324/haematol.2017.181024. Epub 2018 Mar 22. Haematologica. 2018. PMID: 29567771 Free PMC article.
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.
Dierlamm J, Murga Penas EM, Bentink S, Wessendorf S, Berger H, Hummel M, Klapper W, Lenze D, Rosenwald A, Haralambieva E, Ott G, Cogliatti SB, Möller P, Schwaenen C, Stein H, Löffler M, Spang R, Trümper L, Siebert R; Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas". Dierlamm J, et al. Among authors: spang r. Haematologica. 2008 May;93(5):688-96. doi: 10.3324/haematol.12057. Epub 2008 Mar 26. Haematologica. 2008. PMID: 18367485
Inferring cellular networks--a review.
Markowetz F, Spang R. Markowetz F, et al. Among authors: spang r. BMC Bioinformatics. 2007 Sep 27;8 Suppl 6(Suppl 6):S5. doi: 10.1186/1471-2105-8-S6-S5. BMC Bioinformatics. 2007. PMID: 17903286 Free PMC article. Review.
Response-predictive gene expression profiling of glioma progenitor cells in vitro.
Moeckel S, Meyer K, Leukel P, Heudorfer F, Seliger C, Stangl C, Bogdahn U, Proescholdt M, Brawanski A, Vollmann-Zwerenz A, Riemenschneider MJ, Bosserhoff AK, Spang R, Hau P. Moeckel S, et al. Among authors: spang r. PLoS One. 2014 Sep 30;9(9):e108632. doi: 10.1371/journal.pone.0108632. eCollection 2014. PLoS One. 2014. PMID: 25268354 Free PMC article.
Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma.
Engelmann JC, Amann T, Ott-Rötzer B, Nützel M, Reinders Y, Reinders J, Thasler WE, Kristl T, Teufel A, Huber CG, Oefner PJ, Spang R, Hellerbrand C. Engelmann JC, et al. Among authors: spang r. PLoS Comput Biol. 2015 May 28;11(5):e1004293. doi: 10.1371/journal.pcbi.1004293. eCollection 2015 May. PLoS Comput Biol. 2015. PMID: 26020769 Free PMC article.
High-Dimensional Profiling for Computational Diagnosis.
Lottaz C, Gronwald W, Spang R, Engelmann JC. Lottaz C, et al. Among authors: spang r. Methods Mol Biol. 2017;1526:205-229. doi: 10.1007/978-1-4939-6613-4_12. Methods Mol Biol. 2017. PMID: 27896744
Pathway activation patterns in diffuse large B-cell lymphomas.
Bentink S, Wessendorf S, Schwaenen C, Rosolowski M, Klapper W, Rosenwald A, Ott G, Banham AH, Berger H, Feller AC, Hansmann ML, Hasenclever D, Hummel M, Lenze D, Möller P, Stuerzenhofecker B, Loeffler M, Truemper L, Stein H, Siebert R, Spang R; Molecular Mechanisms in Malignant Lymphomas Network Project of the. Bentink S, et al. Among authors: spang r. Leukemia. 2008 Sep;22(9):1746-54. doi: 10.1038/leu.2008.166. Epub 2008 Jun 26. Leukemia. 2008. PMID: 18580954
Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.
Rhein P, Scheid S, Ratei R, Hagemeier C, Seeger K, Kirschner-Schwabe R, Moericke A, Schrappe M, Spang R, Ludwig WD, Karawajew L. Rhein P, et al. Among authors: spang r. Leukemia. 2007 May;21(5):897-905. doi: 10.1038/sj.leu.2404613. Epub 2007 Mar 1. Leukemia. 2007. PMID: 17330098
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