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Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer.
Sabbatini PJ, Ragupathi G, Hood C, Aghajanian CA, Juretzka M, Iasonos A, Hensley ML, Spassova MK, Ouerfelli O, Spriggs DR, Tew WP, Konner J, Clausen H, Abu Rustum N, Dansihefsky SJ, Livingston PO. Sabbatini PJ, et al. Among authors: spassova mk. Clin Cancer Res. 2007 Jul 15;13(14):4170-7. doi: 10.1158/1078-0432.CCR-06-2949. Clin Cancer Res. 2007. PMID: 17634545
A preclinical study comparing approaches for augmenting the immunogenicity of a heptavalent KLH-conjugate vaccine against epithelial cancers.
Ragupathi G, Koide F, Sathyan N, Kagan E, Spassova M, Bornmann W, Gregor P, Reis CA, Clausen H, Danishefsky SJ, Livingston PO. Ragupathi G, et al. Among authors: spassova m. Cancer Immunol Immunother. 2003 Oct;52(10):608-16. doi: 10.1007/s00262-003-0399-2. Epub 2003 Jun 17. Cancer Immunol Immunother. 2003. PMID: 12811527
Carbohydrate vaccines in cancer: immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man.
Slovin SF, Ragupathi G, Adluri S, Ungers G, Terry K, Kim S, Spassova M, Bornmann WG, Fazzari M, Dantis L, Olkiewicz K, Lloyd KO, Livingston PO, Danishefsky SJ, Scher HI. Slovin SF, et al. Among authors: spassova m. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5710-5. doi: 10.1073/pnas.96.10.5710. Proc Natl Acad Sci U S A. 1999. PMID: 10318949 Free PMC article. Clinical Trial.
Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: isolation, quantification, and characterization of immune responses by using totally synthetic immobilized tumor antigens.
Wang ZG, Williams LJ, Zhang XF, Zatorski A, Kudryashov V, Ragupathi G, Spassova M, Bornmann W, Slovin SF, Scher HI, Livingston PO, Lloyd KO, Danishefsky SJ. Wang ZG, et al. Among authors: spassova m. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2719-24. doi: 10.1073/pnas.97.6.2719. Proc Natl Acad Sci U S A. 2000. PMID: 10716997 Free PMC article.
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial.
Gilewski T, Ragupathi G, Bhuta S, Williams LJ, Musselli C, Zhang XF, Bornmann WG, Spassova M, Bencsath KP, Panageas KS, Chin J, Hudis CA, Norton L, Houghton AN, Livingston PO, Danishefsky SJ. Gilewski T, et al. Among authors: spassova m. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3270-5. doi: 10.1073/pnas.051626298. Proc Natl Acad Sci U S A. 2001. PMID: 11248068 Free PMC article. Clinical Trial.
A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission.
O'Cearbhaill RE, Ragupathi G, Zhu J, Wan Q, Mironov S, Yang G, Spassova MK, Iasonos A, Kravetz S, Ouerfelli O, Spriggs DR, Danishefsky SJ, Sabbatini PJ. O'Cearbhaill RE, et al. Among authors: spassova mk. Cancers (Basel). 2016 Apr 22;8(4):46. doi: 10.3390/cancers8040046. Cancers (Basel). 2016. PMID: 27110823 Free PMC article.
A bivalent conjugate vaccine in the treatment of biochemically relapsed prostate cancer: a study of glycosylated MUC-2-KLH and Globo H-KLH conjugate vaccines given with the new semi-synthetic saponin immunological adjuvant GPI-0100 OR QS-21.
Slovin SF, Ragupathi G, Fernandez C, Jefferson MP, Diani M, Wilton AS, Powell S, Spassova M, Reis C, Clausen H, Danishefsky S, Livingston P, Scher HI. Slovin SF, et al. Among authors: spassova m. Vaccine. 2005 May 2;23(24):3114-22. doi: 10.1016/j.vaccine.2005.01.072. Vaccine. 2005. PMID: 15837210
62 results