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Spatial distribution of microbial communities in the cystic fibrosis lung.
Willner D, Haynes MR, Furlan M, Schmieder R, Lim YW, Rainey PB, Rohwer F, Conrad D. Willner D, et al. ISME J. 2012 Feb;6(2):471-4. doi: 10.1038/ismej.2011.104. Epub 2011 Jul 28. ISME J. 2012. PMID: 21796216 Free PMC article.
Cystic fibrosis (CF) is a common fatal genetic disorder with mortality most often resulting from microbial infections of the lungs. ...Microbial communities differed significantly between different areas of the lungs, and few taxa were common to …
Cystic fibrosis (CF) is a common fatal genetic disorder with mortality most often resulting from microbial infections o …
Precise spatial structure impacts antimicrobial susceptibility of S. aureus in polymicrobial wound infections.
Ibberson CB, Barraza JP, Holmes AL, Cao P, Whiteley M. Ibberson CB, et al. Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2212340119. doi: 10.1073/pnas.2212340119. Epub 2022 Dec 15. Proc Natl Acad Sci U S A. 2022. PMID: 36520668 Free PMC article.
A hallmark of microbial ecology is that interactions between members of a community shape community function. This includes microbial communities in human infections, such as chronic wounds, where interactions can result in more severe diseases. ...
A hallmark of microbial ecology is that interactions between members of a community shape community function. This includes microb …
Quantifying microbial chatter: scanning electrochemical microscopy as a tool to study interactions in biofilms.
Darch SE, Koley D. Darch SE, et al. Proc Math Phys Eng Sci. 2018 Dec;474(2220):20180405. doi: 10.1098/rspa.2018.0405. Epub 2018 Dec 12. Proc Math Phys Eng Sci. 2018. PMID: 30602930 Free PMC article. Review.
Bacteria are often found in their natural habitats as spatially organized biofilm communities. While it is clear from recent work that the ability to organize into precise spatial structures is important for fitness of microbial communities, a s …
Bacteria are often found in their natural habitats as spatially organized biofilm communities. While it is clear from recent w …
Multi-species biofilms: living with friendly neighbors.
Elias S, Banin E. Elias S, et al. FEMS Microbiol Rev. 2012 Sep;36(5):990-1004. doi: 10.1111/j.1574-6976.2012.00325.x. Epub 2012 Feb 2. FEMS Microbiol Rev. 2012. PMID: 22229800 Free article. Review.
Our knowledge regarding the nature and development of microbial biofilms has grown significantly since the first report of these communities by Antonie van Leeuwenhoek in the late 1600s. ...The latter, for example, impacts the course and treatment of biofilm-related …
Our knowledge regarding the nature and development of microbial biofilms has grown significantly since the first report of these c …
High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine.
Tomas J, Mulet C, Saffarian A, Cavin JB, Ducroc R, Regnault B, Kun Tan C, Duszka K, Burcelin R, Wahli W, Sansonetti PJ, Pédron T. Tomas J, et al. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):E5934-E5943. doi: 10.1073/pnas.1612559113. Epub 2016 Sep 16. Proc Natl Acad Sci U S A. 2016. PMID: 27638207 Free PMC article.
Little is known about the direct impact of high-fat (HF) diet on small-intestinal mucosal defenses and spatial distribution of the microbiota during the early phase of its administration. We observed that only 30 d after HF diet initiation, the intervillous z …
Little is known about the direct impact of high-fat (HF) diet on small-intestinal mucosal defenses and spatial distribution of …
Three-Dimensional Microbiome and Metabolome Cartography of a Diseased Human Lung.
Garg N, Wang M, Hyde E, da Silva RR, Melnik AV, Protsyuk I, Bouslimani A, Lim YW, Wong R, Humphrey G, Ackermann G, Spivey T, Brouha SS, Bandeira N, Lin GY, Rohwer F, Conrad DJ, Alexandrov T, Knight R, Dorrestein PC. Garg N, et al. Cell Host Microbe. 2017 Nov 8;22(5):705-716.e4. doi: 10.1016/j.chom.2017.10.001. Epub 2017 Oct 19. Cell Host Microbe. 2017. PMID: 29056429 Free PMC article.
To address this challenge, we developed a workflow to enable the cartography of metabolomic and microbiome data onto a three-dimensional (3D) organ reconstruction built off radiological images. This enabled the direct visualization of the microbial and chemical makeup of a …
To address this challenge, we developed a workflow to enable the cartography of metabolomic and microbiome data onto a three-dimensional (3D …