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Porcine cells are susceptible to infection by human alpha herpesviruses.
Leventhal JR, Martinez W, Roszkowski J, Fryer JP, Kaufman DB, Abecassis MI, Stuart FP, Spear P. Leventhal JR, et al. Transplant Proc. 2001 Feb-Mar;33(1-2):691. doi: 10.1016/s0041-1345(00)02205-3. Transplant Proc. 2001. PMID: 11267020 No abstract available.
The virological synapse facilitates herpes simplex virus entry into T cells.
Aubert M, Yoon M, Sloan DD, Spear PG, Jerome KR. Aubert M, et al. Among authors: spear pg. J Virol. 2009 Jun;83(12):6171-83. doi: 10.1128/JVI.02163-08. Epub 2009 Apr 1. J Virol. 2009. PMID: 19339346 Free PMC article.
Binding of herpes simplex virus glycoprotein B (gB) to paired immunoglobulin-like type 2 receptor alpha depends on specific sialylated O-linked glycans on gB.
Wang J, Fan Q, Satoh T, Arii J, Lanier LL, Spear PG, Kawaguchi Y, Arase H. Wang J, et al. Among authors: spear pg. J Virol. 2009 Dec;83(24):13042-5. doi: 10.1128/JVI.00792-09. Epub 2009 Oct 7. J Virol. 2009. PMID: 19812165 Free PMC article.
PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B.
Satoh T, Arii J, Suenaga T, Wang J, Kogure A, Uehori J, Arase N, Shiratori I, Tanaka S, Kawaguchi Y, Spear PG, Lanier LL, Arase H. Satoh T, et al. Cell. 2008 Mar 21;132(6):935-44. doi: 10.1016/j.cell.2008.01.043. Cell. 2008. PMID: 18358807 Free PMC article.
The fusion loops and membrane proximal region of Epstein-Barr virus glycoprotein B (gB) can function in the context of herpes simplex virus 1 gB when substituted individually but not in combination.
Zago A, Connolly SA, Spear PG, Longnecker R. Zago A, et al. Among authors: spear pg. Virus Res. 2013 Jan;171(1):227-30. doi: 10.1016/j.virusres.2012.10.015. Epub 2012 Oct 23. Virus Res. 2013. PMID: 23089849 Free PMC article.
Functional interaction between herpes simplex virus type 2 gD and HVEM transiently dampens local chemokine production after murine mucosal infection.
Yoon M, Kopp SJ, Taylor JM, Storti CS, Spear PG, Muller WJ. Yoon M, et al. Among authors: spear pg. PLoS One. 2011 Jan 24;6(1):e16122. doi: 10.1371/journal.pone.0016122. PLoS One. 2011. PMID: 21283640 Free PMC article.
Insertion mutations in herpes simplex virus 1 glycoprotein H reduce cell surface expression, slow the rate of cell fusion, or abrogate functions in cell fusion and viral entry.
Jackson JO, Lin E, Spear PG, Longnecker R. Jackson JO, et al. Among authors: spear pg. J Virol. 2010 Feb;84(4):2038-46. doi: 10.1128/JVI.02215-09. Epub 2009 Dec 9. J Virol. 2010. PMID: 20007280 Free PMC article.
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