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Epilepsy and cannabidiol: a guide to treatment.
Arzimanoglou A, Brandl U, Cross JH, Gil-Nagel A, Lagae L, Landmark CJ, Specchio N, Nabbout R, Thiele EA, Gubbay O, The Cannabinoids International Experts Panel; Collaborators. Arzimanoglou A, et al. Epileptic Disord. 2020 Feb 1;22(1):1-14. doi: 10.1684/epd.2020.1141. Epileptic Disord. 2020. PMID: 32096470 Free article. Review.
The growing interest in cannabidiol (CBD), specifically a pure form of CBD, as a treatment for epilepsy, among other conditions, is reflected in recent changes in legislation in some countries. ...However, just as we are beginning to understand the significance of …
The growing interest in cannabidiol (CBD), specifically a pure form of CBD, as a treatment for epilepsy, among other condition …
Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy.
Bar-Lev Schleider L, Mechoulam R, Saban N, Meiri G, Novack V. Bar-Lev Schleider L, et al. Sci Rep. 2019 Jan 17;9(1):200. doi: 10.1038/s41598-018-37570-y. Sci Rep. 2019. PMID: 30655581 Free PMC article.
There has been a dramatic increase in the number of children diagnosed with autism spectrum disorders (ASD) worldwide. Recently anecdotal evidence of possible therapeutic effects of cannabis products has emerged. ...The treatment in majority of the patients was based on ca …
There has been a dramatic increase in the number of children diagnosed with autism spectrum disorders (ASD) worldwide. Recently anecd …
Safety, Pharmacokinetics, and Pharmacodynamics of Spectrum Yellow Oil in Healthy Participants.
Peters EN, Mosesova I, MacNair L, Vandrey R, Land MH, Ware MA, Turcotte C, Bonn-Miller MO. Peters EN, et al. J Anal Toxicol. 2021 Mar 12:bkab026. doi: 10.1093/jat/bkab026. Online ahead of print. J Anal Toxicol. 2021. PMID: 33710277
This multiple-dose study evaluated the safety, tolerability, PK, and PD of Spectrum Yellow oil [20 mg/mL cannabidiol (CBD)/<1 mg/mL 9-tetrahydrocannabinol (THC)]. Participants (N=43) were randomized to one of five groups: 120 mg CBD and 5.4 mg THC d …
This multiple-dose study evaluated the safety, tolerability, PK, and PD of Spectrum Yellow oil [20 mg/mL cannabidiol (CBD
A phase I trial of the safety, tolerability and pharmacokinetics of cannabidiol administered as single-dose oil solution and single and multiple doses of a sublingual wafer in healthy volunteers.
Hosseini A, McLachlan AJ, Lickliter JD. Hosseini A, et al. Br J Clin Pharmacol. 2021 Apr;87(4):2070-2077. doi: 10.1111/bcp.14617. Epub 2020 Nov 18. Br J Clin Pharmacol. 2021. PMID: 33075170 Clinical Trial.
METHODS: For the single-dose study, the design was an open-label, 4-way crossover in 12 healthy volunteers randomised to receive a sequence of 4 different single doses of CBD as a sublingual wafer (25 or 50 mg CBD), oil solution (50 mg CBD), or nabixim …
METHODS: For the single-dose study, the design was an open-label, 4-way crossover in 12 healthy volunteers randomised to receive a sequence …
Endocannabinoid System and Its Regulation by Polyunsaturated Fatty Acids and Full Spectrum Hemp Oils.
Komarnytsky S, Rathinasabapathy T, Wagner C, Metzger B, Carlisle C, Panda C, Le Brun-Blashka S, Troup JP, Varadharaj S. Komarnytsky S, et al. Int J Mol Sci. 2021 May 22;22(11):5479. doi: 10.3390/ijms22115479. Int J Mol Sci. 2021. PMID: 34067450 Free PMC article. Review.
Whole food-based diets and dietary interventions linked to PUFAs of animal (fish, calamari, krill) or plant (hemp, flax, walnut, algae) origin, as well as full-spectrum hemp oils, are increasingly used to support the ECS tone, promote healthy metabolism, improve risk facto …
Whole food-based diets and dietary interventions linked to PUFAs of animal (fish, calamari, krill) or plant (hemp, flax, walnut, algae) orig …