Spencer SL - Search Results

1

Measuring and modeling apoptosis in single cells.

Spencer SL, Sorger PK. Spencer SL, et al. Cell. 2011 Mar 18;144(6):926-39. doi: 10.1016/j.cell.2011.03.002. Cell. 2011. PMID: 21414484 Free PMC article. Review.

2

Modeling a snap-action, variable-delay switch controlling extrinsic cell death.

Albeck JG, Burke JM, Spencer SL, Lauffenburger DA, Sorger PK. Albeck JG, et al. Among authors: spencer sl. PLoS Biol. 2008 Dec 2;6(12):2831-52. doi: 10.1371/journal.pbio.0060299. PLoS Biol. 2008. PMID: 19053173 Free PMC article.

3

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.

Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Spencer SL, et al. Nature. 2009 May 21;459(7245):428-32. doi: 10.1038/nature08012. Epub 2009 Apr 12. Nature. 2009. PMID: 19363473 Free PMC article.

4

Non-genetic cell-to-cell variability and the consequences for pharmacology.

Niepel M, Spencer SL, Sorger PK. Niepel M, et al. Among authors: spencer sl. Curr Opin Chem Biol. 2009 Dec;13(5-6):556-61. doi: 10.1016/j.cbpa.2009.09.015. Epub 2009 Oct 14. Curr Opin Chem Biol. 2009. PMID: 19833543 Free PMC article. Review.

5

Systematic calibration of a cell signaling network model.

Kim KA, Spencer SL, Albeck JG, Burke JM, Sorger PK, Gaudet S, Kim DH. Kim KA, et al. Among authors: spencer sl. BMC Bioinformatics. 2010 Apr 23;11:202. doi: 10.1186/1471-2105-11-202. BMC Bioinformatics. 2010. PMID: 20416044 Free PMC article.

6

Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis.

Gaudet S, Spencer SL, Chen WW, Sorger PK. Gaudet S, et al. Among authors: spencer sl. PLoS Comput Biol. 2012;8(4):e1002482. doi: 10.1371/journal.pcbi.1002482. Epub 2012 Apr 26. PLoS Comput Biol. 2012. PMID: 22570596 Free PMC article.

7

Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes.

Flusberg DA, Roux J, Spencer SL, Sorger PK. Flusberg DA, et al. Among authors: spencer sl. Mol Biol Cell. 2013 Jul;24(14):2186-200. doi: 10.1091/mbc.E12-10-0737. Epub 2013 May 22. Mol Biol Cell. 2013. PMID: 23699397 Free PMC article.

8

Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction.

Chen JY, Hug C, Reyes J, Tian C, Gerosa L, Fröhlich F, Ponsioen B, Snippert HJG, Spencer SL, Jambhekar A, Sorger PK, Lahav G. Chen JY, et al. Among authors: spencer sl. Cell Rep. 2023 Mar 28;42(3):112252. doi: 10.1016/j.celrep.2023.112252. Epub 2023 Mar 14. Cell Rep. 2023. PMID: 36920903 Free PMC article.

9

Acute multi-level response to defective de novo chromatin assembly in S-phase.

Dreyer J, Ricci G, van den Berg J, Bhardwaj V, Funk J, Armstrong C, van Batenburg V, Sine C, VanInsberghe MA, Marsman R, Mandemaker IK, di Sanzo S, Costantini J, Manzo SG, Biran A, Burny C, Völker-Albert M, Groth A, Spencer SL, van Oudenaarden A, Mattiroli F. Dreyer J, et al. Among authors: spencer sl. bioRxiv [Preprint]. 2024 Mar 27:2024.03.22.586291. doi: 10.1101/2024.03.22.586291. bioRxiv. 2024. PMID: 38585916 Free PMC article. Preprint.

10

A Highly Anticipated Selective Therapeutic Agent against CDK2: INX-315.

Watts LP, Spencer SL. Watts LP, et al. Among authors: spencer sl. Cancer Discov. 2024 Mar 1;14(3):386-388. doi: 10.1158/2159-8290.CD-23-1537. Cancer Discov. 2024. PMID: 38426558

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