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The X chromosome and male infertility.
Vockel M, Riera-Escamilla A, Tüttelmann F, Krausz C. Vockel M, et al. Hum Genet. 2021 Jan;140(1):203-215. doi: 10.1007/s00439-019-02101-w. Epub 2019 Dec 24. Hum Genet. 2021. PMID: 31875237 Free PMC article. Review.
In this review, we focus on the X chromosome's unique biology as associated with human male infertility. Male infertility is most commonly caused by spermatogenic defects to which X chromosome dosage is closely linked; for example, any supernumerary X chromosome as in Klin …
In this review, we focus on the X chromosome's unique biology as associated with human male infertility. Male infertility is most commonly c …
Medical therapy for spermatogenic failure.
Ramasamy R, Stahl PJ, Schlegel PN. Ramasamy R, et al. Asian J Androl. 2012 Jan;14(1):57-60. doi: 10.1038/aja.2011.63. Epub 2011 Dec 19. Asian J Androl. 2012. PMID: 22179517 Free PMC article. Review.
Medical treatment of men with primary spermatogenic failure remains largely ineffective in contrast to those with secondary testicular failure. ...This review focuses on the rationale and current evidence for hormonal and antioxidant therapy in medical treatm …
Medical treatment of men with primary spermatogenic failure remains largely ineffective in contrast to those with secondary te …
Genetic causes of spermatogenic failure.
Massart A, Lissens W, Tournaye H, Stouffs K. Massart A, et al. Asian J Androl. 2012 Jan;14(1):40-8. doi: 10.1038/aja.2011.67. Epub 2011 Dec 5. Asian J Androl. 2012. PMID: 22138898 Free PMC article. Review.
Advances of three-dimensional (3D) culture systems for in vitro spermatogenesis.
Salem M, Khadivi F, Javanbakht P, Mojaverrostami S, Abbasi M, Feizollahi N, Abbasi Y, Heidarian E, Rezaei Yazdi F. Salem M, et al. Stem Cell Res Ther. 2023 Sep 21;14(1):262. doi: 10.1186/s13287-023-03466-6. Stem Cell Res Ther. 2023. PMID: 37735437 Free PMC article. Review.
The loss of germ cells and spermatogenic failure in non-obstructive azoospermia are believed to be the main causes of male infertility. ...
The loss of germ cells and spermatogenic failure in non-obstructive azoospermia are believed to be the main causes of male inf …
Microdissection testicular sperm extraction (micro-TESE) in men with infertility due to nonobstructive azoospermia: summary of current literature.
Achermann APP, Pereira TA, Esteves SC. Achermann APP, et al. Int Urol Nephrol. 2021 Nov;53(11):2193-2210. doi: 10.1007/s11255-021-02979-4. Epub 2021 Aug 19. Int Urol Nephrol. 2021. PMID: 34410586 Review.
However, geographic locations of testicular sperm producing-areas are uncertain, making microsurgical-guided sperm retrieval (microdissection testicular sperm extraction; micro-TESE) an attractive method to identify and retrieve sperm in patients with NOA due to spermatogenic …
However, geographic locations of testicular sperm producing-areas are uncertain, making microsurgical-guided sperm retrieval (microdissectio …