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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM. Boström P, et al. Among authors: Spiegelman BM. Nature. 2012 Jan 11;481(7382):463-8. doi: 10.1038/nature10777. Nature. 2012. PMID: 22237023 Free PMC article.
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1.
Herzig S, Long F, Jhala US, Hedrick S, Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, Spiegelman B, Montminy M. Herzig S, et al. Among authors: Spiegelman B. Nature. 2001 Sep 13;413(6852):179-83. doi: 10.1038/35093131. Nature. 2001. PMID: 11557984
Activation of PPARgamma coactivator-1 through transcription factor docking.
Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM. Puigserver P, et al. Among authors: Spiegelman BM. Science. 1999 Nov 12;286(5443):1368-71. doi: 10.1126/science.286.5443.1368. Science. 1999. PMID: 10558993
Transcriptional activation of adipogenesis.
Wu Z, Puigserver P, Spiegelman BM. Wu Z, et al. Among authors: Spiegelman BM. Curr Opin Cell Biol. 1999 Dec;11(6):689-94. doi: 10.1016/s0955-0674(99)00037-x. Curr Opin Cell Biol. 1999. PMID: 10600710 Review.
Towards a molecular understanding of adaptive thermogenesis.
Lowell BB, Spiegelman BM. Lowell BB, et al. Among authors: Spiegelman BM. Nature. 2000 Apr 6;404(6778):652-60. doi: 10.1038/35007527. Nature. 2000. PMID: 10766252 Review.
Transcriptional regulation of adipogenesis.
Rosen ED, Walkey CJ, Puigserver P, Spiegelman BM. Rosen ED, et al. Among authors: Spiegelman BM. Genes Dev. 2000 Jun 1;14(11):1293-307. Genes Dev. 2000. PMID: 10837022 Review. No abstract available.
The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.
Moore KJ, Rosen ED, Fitzgerald ML, Randow F, Andersson LP, Altshuler D, Milstone DS, Mortensen RM, Spiegelman BM, Freeman MW. Moore KJ, et al. Among authors: Spiegelman BM. Nat Med. 2001 Jan;7(1):41-7. doi: 10.1038/83328. Nat Med. 2001. PMID: 11135614
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