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Spinosad: in pediculosis capitis.
McCormack PL. McCormack PL. Am J Clin Dermatol. 2011 Oct 1;12(5):349-53. doi: 10.2165/11208070-000000000-00000. Am J Clin Dermatol. 2011. PMID: 21834600 Review.
Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. ...Spinosad 0.9% kills both permethrin-susceptible and permethrin-resistant populations of lice. ...
Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. ...Spinosad 0.9% kills bo …
Properties, toxicity and current applications of the biolarvicide spinosad.
Santos VSV, Pereira BB. Santos VSV, et al. J Toxicol Environ Health B Crit Rev. 2020;23(1):13-26. doi: 10.1080/10937404.2019.1689878. Epub 2019 Nov 11. J Toxicol Environ Health B Crit Rev. 2020. PMID: 31709913 Review.
Characterized as a highly valuable bioactive natural product, spinosad is a pesticide with a complex chemical structure, composed of spinosyn A and D, molecules synthesized by the actinomycete Saccharopolyspora spinosa. The larvicidal activity of spinosad was postul …
Characterized as a highly valuable bioactive natural product, spinosad is a pesticide with a complex chemical structure, composed of …
Pesticide Research and Development: General Discussion and Spinosad Case.
Chio EH, Li QX. Chio EH, et al. J Agric Food Chem. 2022 Jul 27;70(29):8913-8919. doi: 10.1021/acs.jafc.2c03821. Epub 2022 Jul 14. J Agric Food Chem. 2022. PMID: 35834192 Review.
In this perspective, pesticide R/D is briefly discussed and a case study is used to illustrate how spinosad was discovered and became a successful product, despite the many challenges facing pesticide R/D....
In this perspective, pesticide R/D is briefly discussed and a case study is used to illustrate how spinosad was discovered and became …
Strategies for Enhancing the Yield of the Potent Insecticide Spinosad in Actinomycetes.
Tao H, Zhang Y, Deng Z, Liu T. Tao H, et al. Biotechnol J. 2019 Jan;14(1):e1700769. doi: 10.1002/biot.201700769. Epub 2018 Jul 5. Biotechnol J. 2019. PMID: 29897659 Review.
Spinosad is a potent insecticide that exhibits an excellent environmental and mammalian profile. However, spinosad production in the original producer, Saccharopolyspora spinosa, is insufficient for the huge global demand. ...
Spinosad is a potent insecticide that exhibits an excellent environmental and mammalian profile. However, spinosad production …
Spinosad blocks CHRNA5 mediated EGFR signaling pathway activation to inhibit lung adenocarcinoma proliferation.
Zou H, Chen Y, Zhu X, Zhao X, Cao J, Chen Y, Zhang Z, Zhu Y, Li Q, Li M. Zou H, et al. Biomed Pharmacother. 2024 Aug;177:117105. doi: 10.1016/j.biopha.2024.117105. Epub 2024 Jul 14. Biomed Pharmacother. 2024. PMID: 39002438 Free article.
In this study, a screening of 17 nicotinic acetylcholine receptor allosteric agents revealed that spinosad effectively suppressed the proliferation of LUAD cells. The experiments demonstrated that spinosad induced cell cycle arrest in the G1 phase and stimulated apo …
In this study, a screening of 17 nicotinic acetylcholine receptor allosteric agents revealed that spinosad effectively suppressed the …
The spinosyns, spinosad, spinetoram, and synthetic spinosyn mimics - discovery, exploration, and evolution of a natural product chemistry and the impact of computational tools.
Sparks TC, Crouse GD, Benko Z, Demeter D, Giampietro NC, Lambert W, Brown AV. Sparks TC, et al. Pest Manag Sci. 2021 Aug;77(8):3637-3649. doi: 10.1002/ps.6073. Epub 2020 Sep 28. Pest Manag Sci. 2021. PMID: 32893433 Review.
More than 20 years after initial registration, the spinosyns remain a unique class of NP-based insect control products that presently encompass two insecticidal active ingredients, spinosad, a naturally occurring mixture of spinosyns, and spinetoram, a semi-synthetic spino …
More than 20 years after initial registration, the spinosyns remain a unique class of NP-based insect control products that presently encomp …
Spinosad topical suspension (0.9%): a new topical treatment for scabies.
Fernando DD, Fischer K. Fernando DD, et al. Expert Rev Anti Infect Ther. 2022 Sep;20(9):1149-1154. doi: 10.1080/14787210.2022.2099376. Epub 2022 Aug 9. Expert Rev Anti Infect Ther. 2022. PMID: 35799317
Consequently, new single-dose scabicides are urgently needed. AREAS COVERED: In 2021, spinosad, a drug previously used to treat head lice, was approved by the US FDA as a topical scabies treatment. ...EXPERT OPINION: As the first single-dose scabicide, the formulated 0.9% …
Consequently, new single-dose scabicides are urgently needed. AREAS COVERED: In 2021, spinosad, a drug previously used to treat head …
Spinosad for the treatment of head lice infestations.
Villegas SC. Villegas SC. Drugs Today (Barc). 2012 Sep;48(9):595-9. doi: 10.1358/dot.2012.48.9.1844809. Drugs Today (Barc). 2012. PMID: 23032800 Review.
In clinical trials, it has demonstrated effectiveness against head lice with permethrin resistance. In two clinical trials comparing spinosad to permethrin, efficacy was observed in the spinosad-treated groups at 84.6% and 86.7%, respectively, when compared to the p …
In clinical trials, it has demonstrated effectiveness against head lice with permethrin resistance. In two clinical trials comparing spin …
Temperature and spinosad-induced modulation of antioxidant enzyme activity and gene expression of adaptive stress-related genes in Ceratitis capitata.
Fouda M, Negm A, Germoush M, Mahmoud S. Fouda M, et al. Open Vet J. 2025 Jan;15(1):108-117. doi: 10.5455/OVJ.2025.v15.i1.10. Epub 2025 Jan 31. Open Vet J. 2025. PMID: 40092184 Free PMC article. Review.
Adults were exposed to three conditions; high temperature (40AC); spinosad at its LC(50) (3.2 Ag/ml) at 25AC, and combined spinosad exposure and high temperature. ...The combined treatment of spinosad and heat stress amplified these effects, indicating a syne …
Adults were exposed to three conditions; high temperature (40AC); spinosad at its LC(50) (3.2 Ag/ml) at 25AC, and combined spinosa …
1,147 results