Spires-Jones TL - Search Results

1

Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain.

Kopeikina KJ, Carlson GA, Pitstick R, Ludvigson AE, Peters A, Luebke JI, Koffie RM, Frosch MP, Hyman BT, Spires-Jones TL. Kopeikina KJ, et al. Am J Pathol. 2011 Oct;179(4):2071-82. doi: 10.1016/j.ajpath.2011.07.004. Epub 2011 Aug 18. Am J Pathol. 2011. PMID: 21854751 Free PMC article.

2

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model.

Spires-Jones TL, Meyer-Luehmann M, Osetek JD, Jones PB, Stern EA, Bacskai BJ, Hyman BT. Spires-Jones TL, et al. Am J Pathol. 2007 Oct;171(4):1304-11. doi: 10.2353/ajpath.2007.070055. Epub 2007 Aug 23. Am J Pathol. 2007. PMID: 17717139 Free PMC article.

3

TAR-DNA binding protein 43 in Pick disease.

Freeman SH, Spires-Jones T, Hyman BT, Growdon JH, Frosch MP. Freeman SH, et al. J Neuropathol Exp Neurol. 2008 Jan;67(1):62-7. doi: 10.1097/nen.0b013e3181609361. J Neuropathol Exp Neurol. 2008. PMID: 18091558

4

In vivo imaging reveals dissociation between caspase activation and acute neuronal death in tangle-bearing neurons.

Spires-Jones TL, de Calignon A, Matsui T, Zehr C, Pitstick R, Wu HY, Osetek JD, Jones PB, Bacskai BJ, Feany MB, Carlson GA, Ashe KH, Lewis J, Hyman BT. Spires-Jones TL, et al. J Neurosci. 2008 Jan 23;28(4):862-7. doi: 10.1523/JNEUROSCI.3072-08.2008. J Neurosci. 2008. PMID: 18216194 Free PMC article.

5

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease.

Meyer-Luehmann M, Spires-Jones TL, Prada C, Garcia-Alloza M, de Calignon A, Rozkalne A, Koenigsknecht-Talboo J, Holtzman DM, Bacskai BJ, Hyman BT. Meyer-Luehmann M, et al. Nature. 2008 Feb 7;451(7179):720-4. doi: 10.1038/nature06616. Nature. 2008. PMID: 18256671 Free PMC article.

6

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy.

Jones PB, Rozkalne A, Meyer-Luehmann M, Spires-Jones TL, Makarova A, Kumar AT, Berezovska O, Bacskai BB, Hyman BT. Jones PB, et al. J Biomed Opt. 2008 Jan-Feb;13(1):014008. doi: 10.1117/1.2837169. J Biomed Opt. 2008. PMID: 18315366 Free article.

7

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease.

Spires-Jones TL, Mielke ML, Rozkalne A, Meyer-Luehmann M, de Calignon A, Bacskai BJ, Schenk D, Hyman BT. Spires-Jones TL, et al. Neurobiol Dis. 2009 Feb;33(2):213-20. doi: 10.1016/j.nbd.2008.10.011. Epub 2008 Nov 6. Neurobiol Dis. 2009. PMID: 19028582 Free PMC article.

8

Tau pathophysiology in neurodegeneration: a tangled issue.

Spires-Jones TL, Stoothoff WH, de Calignon A, Jones PB, Hyman BT. Spires-Jones TL, et al. Trends Neurosci. 2009 Mar;32(3):150-9. doi: 10.1016/j.tins.2008.11.007. Epub 2009 Jan 21. Trends Neurosci. 2009. PMID: 19162340 Review.

9

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques.

Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M, Micheva KD, Smith SJ, Kim ML, Lee VM, Hyman BT, Spires-Jones TL. Koffie RM, et al. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4012-7. doi: 10.1073/pnas.0811698106. Epub 2009 Feb 19. Proc Natl Acad Sci U S A. 2009. PMID: 19228947 Free PMC article.

10

A single dose of passive immunotherapy has extended benefits on synapses and neurites in an Alzheimer's disease mouse model.

Rozkalne A, Spires-Jones TL, Stern EA, Hyman BT. Rozkalne A, et al. Brain Res. 2009 Jul 14;1280:178-85. doi: 10.1016/j.brainres.2009.05.045. Epub 2009 May 22. Brain Res. 2009. PMID: 19465012 Free PMC article.

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