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The EU-AIMS Longitudinal European Autism Project (LEAP): design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders.
Loth E, Charman T, Mason L, Tillmann J, Jones EJH, Wooldridge C, Ahmad J, Auyeung B, Brogna C, Ambrosino S, Banaschewski T, Baron-Cohen S, Baumeister S, Beckmann C, Brammer M, Brandeis D, Bölte S, Bourgeron T, Bours C, de Bruijn Y, Chakrabarti B, Crawley D, Cornelissen I, Acqua FD, Dumas G, Durston S, Ecker C, Faulkner J, Frouin V, Garces P, Goyard D, Hayward H, Ham LM, Hipp J, Holt RJ, Johnson MH, Isaksson J, Kundu P, Lai MC, D'ardhuy XL, Lombardo MV, Lythgoe DJ, Mandl R, Meyer-Lindenberg A, Moessnang C, Mueller N, O'Dwyer L, Oldehinkel M, Oranje B, Pandina G, Persico AM, Ruigrok ANV, Ruggeri B, Sabet J, Sacco R, Cáceres ASJ, Simonoff E, Toro R, Tost H, Waldman J, Williams SCR, Zwiers MP, Spooren W, Murphy DGM, Buitelaar JK. Loth E, et al. Among authors: spooren w. Mol Autism. 2017 Jun 23;8:24. doi: 10.1186/s13229-017-0146-8. eCollection 2017. Mol Autism. 2017. PMID: 28649312 Free PMC article.
Patients with autism spectrum disorders display reproducible functional connectivity alterations.
Holiga Š, Hipp JF, Chatham CH, Garces P, Spooren W, D'Ardhuy XL, Bertolino A, Bouquet C, Buitelaar JK, Bours C, Rausch A, Oldehinkel M, Bouvard M, Amestoy A, Caralp M, Gueguen S, Ly-Le Moal M, Houenou J, Beckmann CF, Loth E, Murphy D, Charman T, Tillmann J, Laidi C, Delorme R, Beggiato A, Gaman A, Scheid I, Leboyer M, d'Albis MA, Sevigny J, Czech C, Bolognani F, Honey GD, Dukart J. Holiga Š, et al. Among authors: spooren w. Sci Transl Med. 2019 Feb 27;11(481):eaat9223. doi: 10.1126/scitranslmed.aat9223. Sci Transl Med. 2019. PMID: 30814340
Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder.
Brunner D, Kabitzke P, He D, Cox K, Thiede L, Hanania T, Sabath E, Alexandrov V, Saxe M, Peles E, Mills A, Spooren W, Ghosh A, Feliciano P, Benedetti M, Luo Clayton A, Biemans B. Brunner D, et al. Among authors: spooren w. PLoS One. 2015 Aug 14;10(8):e0134572. doi: 10.1371/journal.pone.0134572. eCollection 2015. PLoS One. 2015. PMID: 26273832 Free PMC article.
Identification and validation of biomarkers for autism spectrum disorders.
Loth E, Spooren W, Ham LM, Isaac MB, Auriche-Benichou C, Banaschewski T, Baron-Cohen S, Broich K, Bölte S, Bourgeron T, Charman T, Collier D, de Andres-Trelles F, Durston S, Ecker C, Elferink A, Haberkamp M, Hemmings R, Johnson MH, Jones EJ, Khwaja OS, Lenton S, Mason L, Mantua V, Meyer-Lindenberg A, Lombardo MV, O'Dwyer L, Okamoto K, Pandina GJ, Pani L, Persico AM, Simonoff E, Tauscher-Wisniewski S, Llinares-Garcia J, Vamvakas S, Williams S, Buitelaar JK, Murphy DG. Loth E, et al. Among authors: spooren w. Nat Rev Drug Discov. 2016 Jan;15(1):70-3. doi: 10.1038/nrd.2015.7. Nat Rev Drug Discov. 2016. PMID: 26718285 No abstract available.
New treatment targets for autism spectrum disorders: EU-AIMS.
Loth E, Spooren W, Murphy DG; EU-AIMS consortium. Loth E, et al. Among authors: spooren w. Lancet Psychiatry. 2014 Nov;1(6):413-5. doi: 10.1016/S2215-0366(14)00004-2. Epub 2014 Nov 5. Lancet Psychiatry. 2014. PMID: 26361185 No abstract available.
Investigating the factors underlying adaptive functioning in autism in the EU-AIMS Longitudinal European Autism Project.
Tillmann J, San José Cáceres A, Chatham CH, Crawley D, Holt R, Oakley B, Banaschewski T, Baron-Cohen S, Bölte S, Buitelaar JK, Durston S, Ham L, Loth E, Simonoff E, Spooren W, Murphy DG, Charman T; EU-AIMS LEAP group. Tillmann J, et al. Among authors: spooren w. Autism Res. 2019 Apr;12(4):645-657. doi: 10.1002/aur.2081. Epub 2019 Feb 11. Autism Res. 2019. PMID: 30741482 Free PMC article.
Altered Connectivity Between Cerebellum, Visual, and Sensory-Motor Networks in Autism Spectrum Disorder: Results from the EU-AIMS Longitudinal European Autism Project.
Oldehinkel M, Mennes M, Marquand A, Charman T, Tillmann J, Ecker C, Dell'Acqua F, Brandeis D, Banaschewski T, Baumeister S, Moessnang C, Baron-Cohen S, Holt R, Bölte S, Durston S, Kundu P, Lombardo MV, Spooren W, Loth E, Murphy DGM, Beckmann CF, Buitelaar JK; EU-AIMS LEAP group. Oldehinkel M, et al. Among authors: spooren w. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Mar;4(3):260-270. doi: 10.1016/j.bpsc.2018.11.010. Epub 2018 Dec 5. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019. PMID: 30711508
106 results