Spruck CH - Search Results

1

Deregulated cyclin E induces chromosome instability.

Spruck CH, Won KA, Reed SI. Spruck CH, et al. Nature. 1999 Sep 16;401(6750):297-300. doi: 10.1038/45836. Nature. 1999. PMID: 10499591

2

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, Krek TW, Reed SI. Spruck C, et al. Mol Cell. 2001 Mar;7(3):639-50. doi: 10.1016/s1097-2765(01)00210-6. Mol Cell. 2001. PMID: 11463388

3

Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.

del Rincón SV, Widschwendter M, Sun D, Ekholm-Reed S, Tat J, Teixeira LK, Ellederova Z, Grolieres E, Reed SI, Spruck C. del Rincón SV, et al. Oncogene. 2015 Apr 9;34(15):1961-7. doi: 10.1038/onc.2014.137. Epub 2014 May 26. Oncogene. 2015. PMID: 24858038 Free PMC article.

4

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.

Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Strohmaier H, et al. Among authors: spruck ch. Nature. 2001 Sep 20;413(6853):316-22. doi: 10.1038/35095076. Nature. 2001. PMID: 11565034

5

p16 gene in uncultured tumours.

Spruck CH 3rd, Gonzalez-Zulueta M, Shibata A, Simoneau AR, Lin MF, Gonzales F, Tsai YC, Jones PA. Spruck CH 3rd, et al. Nature. 1994 Jul 21;370(6486):183-4. doi: 10.1038/370183a0. Nature. 1994. PMID: 8028660 No abstract available.

6

FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma.

Suryo Rahmanto A, Savov V, Brunner A, Bolin S, Weishaupt H, Malyukova A, Rosén G, Čančer M, Hutter S, Sundström A, Kawauchi D, Jones DT, Spruck C, Taylor MD, Cho YJ, Pfister SM, Kool M, Korshunov A, Swartling FJ, Sangfelt O. Suryo Rahmanto A, et al. EMBO J. 2016 Oct 17;35(20):2192-2212. doi: 10.15252/embj.201693889. Epub 2016 Sep 13. EMBO J. 2016. PMID: 27625374 Free PMC article.

7

PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.

Tan Y, Sun D, Jiang W, Klotz-Noack K, Vashisht AA, Wohlschlegel J, Widschwendter M, Spruck C. Tan Y, et al. Cancer Res. 2014 Apr 1;74(7):2006-14. doi: 10.1158/0008-5472.CAN-13-1263. Epub 2014 Feb 7. Cancer Res. 2014. PMID: 24509904 Free PMC article.

8

CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.

Cepeda D, Ng HF, Sharifi HR, Mahmoudi S, Cerrato VS, Fredlund E, Magnusson K, Nilsson H, Malyukova A, Rantala J, Klevebring D, Viñals F, Bhaskaran N, Zakaria SM, Rahmanto AS, Grotegut S, Nielsen ML, Szigyarto CA, Sun D, Lerner M, Navani S, Widschwendter M, Uhlén M, Jirström K, Pontén F, Wohlschlegel J, Grandér D, Spruck C, Larsson LG, Sangfelt O. Cepeda D, et al. EMBO Mol Med. 2013 Jul;5(7):1067-86. doi: 10.1002/emmm.201202341. Epub 2013 Jun 14. EMBO Mol Med. 2013. PMID: 23776131 Free PMC article.

9

Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.

Spruck C, Sun D, Fiegl H, Marth C, Mueller-Holzner E, Goebel G, Widschwendter M, Reed SI. Spruck C, et al. Cancer Res. 2006 Jul 15;66(14):7355-60. doi: 10.1158/0008-5472.CAN-05-3240. Cancer Res. 2006. PMID: 16849587

10

Cyclin E dysregulation and chromosomal instability in endometrial cancer.

Hubalek MM, Widschwendter A, Erdel M, Gschwendtner A, Fiegl HM, Müller HM, Goebel G, Mueller-Holzner E, Marth C, Spruck CH, Reed SI, Widschwendter M. Hubalek MM, et al. Among authors: spruck ch. Oncogene. 2004 May 20;23(23):4187-92. doi: 10.1038/sj.onc.1207560. Oncogene. 2004. PMID: 15048079

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