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Cholinergic receptor signaling modulates spontaneous firing of sinoatrial nodal cells via integrated effects on PKA-dependent Ca(2+) cycling and I(KACh).
Lyashkov AE, Vinogradova TM, Zahanich I, Li Y, Younes A, Nuss HB, Spurgeon HA, Maltsev VA, Lakatta EG. Lyashkov AE, et al. Among authors: spurgeon ha. Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H949-59. doi: 10.1152/ajpheart.01340.2008. Epub 2009 Jun 19. Am J Physiol Heart Circ Physiol. 2009. PMID: 19542482 Free PMC article.
New evidence for coupled clock regulation of the normal automaticity of sinoatrial nodal pacemaker cells: bradycardic effects of ivabradine are linked to suppression of intracellular Ca²⁺ cycling.
Yaniv Y, Sirenko S, Ziman BD, Spurgeon HA, Maltsev VA, Lakatta EG. Yaniv Y, et al. Among authors: spurgeon ha. J Mol Cell Cardiol. 2013 Sep;62:80-9. doi: 10.1016/j.yjmcc.2013.04.026. Epub 2013 May 5. J Mol Cell Cardiol. 2013. PMID: 23651631 Free PMC article.
Electrochemical Na+ and Ca2+ gradients drive coupled-clock regulation of automaticity of isolated rabbit sinoatrial nodal pacemaker cells.
Sirenko SG, Maltsev VA, Yaniv Y, Bychkov R, Yaeger D, Vinogradova T, Spurgeon HA, Lakatta EG. Sirenko SG, et al. Among authors: spurgeon ha. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H251-67. doi: 10.1152/ajpheart.00667.2015. Epub 2016 May 20. Am J Physiol Heart Circ Physiol. 2016. PMID: 27208164 Free PMC article.
93 results