Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

138 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non-DR3 or non-DR5/7.
Spurkland A, Sollid LM, Polanco I, Vartdal F, Thorsby E. Spurkland A, et al. Hum Immunol. 1992 Nov;35(3):188-92. doi: 10.1016/0198-8859(92)90104-u. Hum Immunol. 1992. PMID: 1293082
The susceptibility to develop celiac disease (CD) seems to be primarily associated to a particular HLA-DQ alpha/beta heterodimer encoded by the DQA1*0501 and DQB1*0201 alleles, in cis position on the DR3-DQ2 haplotype or in trans position by DR5-DQ7/DR7-DQ2 heterozygotes. …
The susceptibility to develop celiac disease (CD) seems to be primarily associated to a particular HLA-DQ alpha/beta heterodimer enco …
CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell-Specific Adaptor Protein.
Hem CD, Ekornhol M, Granum S, Sundvold-Gjerstad V, Spurkland A. Hem CD, et al. Among authors: spurkland a. Scand J Immunol. 2017 Feb;85(2):104-112. doi: 10.1111/sji.12513. Scand J Immunol. 2017. PMID: 27896837
The T cell-specific adaptor protein (TSAd) contains several protein interaction domains, and is merging as a modulator of T cell activation. ...Via its Src homology 2 (SH2) domain, TSAd may thus function as a link between these enzymes and other signalling molecules …
The T cell-specific adaptor protein (TSAd) contains several protein interaction domains, and is merging as a modulator of T cell acti …
Expression of the T cell-specific adapter protein in human tissues.
Pandya AD, Leergaard TB, Dissen E, Haraldsen G, Spurkland A. Pandya AD, et al. Among authors: spurkland a. Scand J Immunol. 2014 Sep;80(3):169-79. doi: 10.1111/sji.12199. Scand J Immunol. 2014. PMID: 24910151
Immunostaining of adjacent tissue sections revealed that a substantial fraction of CD3-positive cells in normal lymphoid and non-lymphoid tissues expressed TSAd. ...
Immunostaining of adjacent tissue sections revealed that a substantial fraction of CD3-positive cells in normal lymphoid and non-lymp …
Molecular genetic studies of natives on Easter Island: evidence of an early European and Amerindian contribution to the Polynesian gene pool.
Lie BA, Dupuy BM, Spurkland A, Fernández-Viña MA, Hagelberg E, Thorsby E. Lie BA, et al. Among authors: spurkland a. Tissue Antigens. 2007 Jan;69(1):10-8. doi: 10.1111/j.1399-0039.2006.00717.x. Tissue Antigens. 2007. PMID: 17212703
All individuals carried mtDNA types and HLA alleles previously found in Polynesia, and most men carried Y chromosome markers of Polynesian origin, providing further evidence of a Polynesian origin of the population of Easter Island. A few individuals carried HLA all …
All individuals carried mtDNA types and HLA alleles previously found in Polynesia, and most men carried Y chromosome markers of Polynesian o …
Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography.
Etokebe GE, Abrahamsen TG, Bogen B, Spurkland A. Etokebe GE, et al. Among authors: spurkland a. Scand J Immunol. 2004 May;59(5):496-503. doi: 10.1111/j.0300-9475.2004.01422.x. Scand J Immunol. 2004. PMID: 15140060
Denaturing high-performance liquid chromatography (DHPLC) was evaluated as a tool for diagnostic screening of polymorphisms in the tumour necrosis factor receptor superfamily member 6 (TNFRSF6) also known as CD95, Apo-1 or Fas gene. ...In conclusion, DHPLC is a suit …
Denaturing high-performance liquid chromatography (DHPLC) was evaluated as a tool for diagnostic screening of polymorphisms in the tu …
The HLA-DR3,DQ2 heterozygous genotype is associated with an accelerated progression of primary sclerosing cholangitis.
Boberg KM, Spurkland A, Rocca G, Egeland T, Saarinen S, Mitchell S, Broomé U, Chapman R, Olerup O, Pares A, Rosina F, Schrumpf E. Boberg KM, et al. Among authors: spurkland a. Scand J Gastroenterol. 2001 Aug;36(8):886-90. doi: 10.1080/003655201750313441. Scand J Gastroenterol. 2001. PMID: 11495087
The presence of a DQ6 encoding haplotype (DQB1*0603 or DQB1*0602) in DR3,DQ2 negative individuals was associated with a reduced risk of death or liver transplantation (hazard ratio = 0.57; 95% CI = 0.36-0.88). ...CONCLUSION: The DR3,DQ2 heterozygous genotype is asso …
The presence of a DQ6 encoding haplotype (DQB1*0603 or DQB1*0602) in DR3,DQ2 negative individuals was associated with a reduce …
Genetic association between juvenile rheumatoid arthritis and polymorphism in the SH2D2A gene.
Smerdel A, Dai KZ, Lorentzen AR, Flatø B, Maslinski S, Thorsby E, Førre Ø, Spurkland A. Smerdel A, et al. Among authors: spurkland a. Genes Immun. 2004 Jun;5(4):310-2. doi: 10.1038/sj.gene.6364093. Genes Immun. 2004. PMID: 15129233
There was a significant increased frequency of HLA-DRB1(*)08-positive patients carrying two copies of 'short' alleles GA(13) and/or GA(16) compared to healthy controls (16% vs 6%; P(n=4)=0.016). ...
There was a significant increased frequency of HLA-DRB1(*)08-positive patients carrying two copies of 'short' alleles GA(13) and/or G …
The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis.
Dai KZ, Harbo HF, Celius EG, Oturai A, Sørensen PS, Ryder LP, Datta P, Svejgaard A, Hillert J, Fredrikson S, Sandberg-Wollheim M, Laaksonen M, Myhr KM, Nyland H, Vartdal F, Spurkland A. Dai KZ, et al. Among authors: spurkland a. Genes Immun. 2001 Aug;2(5):263-8. doi: 10.1038/sj.gene.6363774. Genes Immun. 2001. PMID: 11528519
We therefore evaluated whether a polymorphic GA repeat (GA(13)-GA(33)) within the promoter region of the SH2D2A gene shows association to multiple sclerosis (MS). ...Since the SH2D2A protein modulates T cell activation, this may be a mechanism for how short SH2D2A a …
We therefore evaluated whether a polymorphic GA repeat (GA(13)-GA(33)) within the promoter region of the SH2D2A gene shows associatio …
T cell-specific adapter protein inhibits T cell activation by modulating Lck activity.
Sundvold V, Torgersen KM, Post NH, Marti F, King PD, Røttingen JA, Spurkland A, Lea T. Sundvold V, et al. Among authors: spurkland a. J Immunol. 2000 Sep 15;165(6):2927-31. doi: 10.4049/jimmunol.165.6.2927. J Immunol. 2000. PMID: 10975797
We previously reported the isolation of a cDNA encoding a T cell-specific adapter protein (TSAd). Its amino acid sequence contains an SH2 domain, tyrosines in protein binding motifs, and proline-rich regions. ...Furthermore, TSAd inhibited Zap-70 recruitment to the …
We previously reported the isolation of a cDNA encoding a T cell-specific adapter protein (TSAd). Its amino acid sequence cont …
138 results
Jump to page
Feedback