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Page 1
Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone.
Owen KL, Gearing LJ, Zanker DJ, Brockwell NK, Khoo WH, Roden DL, Cmero M, Mangiola S, Hong MK, Spurling AJ, McDonald M, Chan CL, Pasam A, Lyons RJ, Duivenvoorden HM, Ryan A, Butler LM, Mariadason JM, Giang Phan T, Hayes VM, Sandhu S, Swarbrick A, Corcoran NM, Hertzog PJ, Croucher PI, Hovens C, Parker BS. Owen KL, et al. Among authors: spurling aj. EMBO Rep. 2020 Jun 4;21(6):e50162. doi: 10.15252/embr.202050162. Epub 2020 Apr 21. EMBO Rep. 2020. PMID: 32314873 Free PMC article.
Intratumoral administration of the Toll-like receptor 7/8 agonist 3M-052 enhances interferon-driven tumor immunogenicity and suppresses metastatic spread in preclinical triple-negative breast cancer.
Zanker DJ, Spurling AJ, Brockwell NK, Owen KL, Zakhour JM, Robinson T, Duivenvoorden HM, Hertzog PJ, Mullins SR, Wilkinson RW, Parker BS. Zanker DJ, et al. Among authors: spurling aj. Clin Transl Immunology. 2020 Sep 28;9(9):e1177. doi: 10.1002/cti2.1177. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33005415 Free PMC article.
Neoadjuvant Interferons: Critical for Effective PD-1-Based Immunotherapy in TNBC.
Brockwell NK, Owen KL, Zanker D, Spurling A, Rautela J, Duivenvoorden HM, Baschuk N, Caramia F, Loi S, Darcy PK, Lim E, Parker BS. Brockwell NK, et al. Cancer Immunol Res. 2017 Oct;5(10):871-884. doi: 10.1158/2326-6066.CIR-17-0150. Epub 2017 Aug 28. Cancer Immunol Res. 2017. PMID: 28848054
Myoepithelial cell-specific expression of stefin A as a suppressor of early breast cancer invasion.
Duivenvoorden HM, Rautela J, Edgington-Mitchell LE, Spurling A, Greening DW, Nowell CJ, Molloy TJ, Robbins E, Brockwell NK, Lee CS, Chen M, Holliday A, Selinger CI, Hu M, Britt KL, Stroud DA, Bogyo M, Möller A, Polyak K, Sloane BF, O'Toole SA, Parker BS. Duivenvoorden HM, et al. J Pathol. 2017 Dec;243(4):496-509. doi: 10.1002/path.4990. Epub 2017 Oct 31. J Pathol. 2017. PMID: 29086922
Tumor inherent interferon regulators as biomarkers of long-term chemotherapeutic response in TNBC.
Brockwell NK, Rautela J, Owen KL, Gearing LJ, Deb S, Harvey K, Spurling A, Zanker D, Chan CL, Cumming HE, Deng N, Zakhour JM, Duivenvoorden HM, Robinson T, Harris M, White M, Fox J, Ooi C, Kumar B, Thomson J, Potasz N, Swarbrick A, Hertzog PJ, Molloy TJ, Toole SO, Ganju V, Parker BS. Brockwell NK, et al. NPJ Precis Oncol. 2019 Aug 29;3:21. doi: 10.1038/s41698-019-0093-2. eCollection 2019. NPJ Precis Oncol. 2019. PMID: 31482136 Free PMC article.
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis.
Samuel M, Fonseka P, Sanwlani R, Gangoda L, Chee SH, Keerthikumar S, Spurling A, Chitti SV, Zanker D, Ang CS, Atukorala I, Kang T, Shahi S, Marzan AL, Nedeva C, Vennin C, Lucas MC, Cheng L, Herrmann D, Pathan M, Chisanga D, Warren SC, Zhao K, Abraham N, Anand S, Boukouris S, Adda CG, Jiang L, Shekhar TM, Baschuk N, Hawkins CJ, Johnston AJ, Orian JM, Hoogenraad NJ, Poon IK, Hill AF, Jois M, Timpson P, Parker BS, Mathivanan S. Samuel M, et al. Among authors: spurling a. Nat Commun. 2021 Jun 24;12(1):3950. doi: 10.1038/s41467-021-24273-8. Nat Commun. 2021. PMID: 34168137 Free PMC article.
Colorimetric histology using plasmonically active microscope slides.
Balaur E, O' Toole S, Spurling AJ, Mann GB, Yeo B, Harvey K, Sadatnajafi C, Hanssen E, Orian J, Nugent KA, Parker BS, Abbey B. Balaur E, et al. Among authors: spurling aj. Nature. 2021 Oct;598(7879):65-71. doi: 10.1038/s41586-021-03835-2. Epub 2021 Oct 6. Nature. 2021. PMID: 34616057
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