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Horizontal DNA and mRNA transfer between donor and recipient cells after allogeneic hematopoietic cell transplantation?
Waterhouse M, Themeli M, Metaxas Y, Lagadinou ED, Finke J, Spyridonidis A. Waterhouse M, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14:2704-13. doi: 10.2741/3407. Front Biosci (Landmark Ed). 2009. PMID: 19273229 Review.
The current review discusses existing data on these recently discovered phenomena and focuses on horizontal gene transfer between donor and recipient cells as a possible mechanism explaining and linking these phenomena....
The current review discusses existing data on these recently discovered phenomena and focuses on horizontal gene transfer between donor and …
Correction: Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients.
Spyridonidis A, Labopin M, Savani BN, Niittyvuopio R, Blaise D, Craddock C, Socié G, Platzbecker U, Beelen D, Milpied N, Cornelissen JJ, Ganser A, Huynh A, Griskevicius L, Giebel S, Aljurf M, Brissot E, Malard F, Esteve J, Peric Z, Baron F, Ruggeri A, Schmid C, Gilleece M, Gorin NC, Lanza F, Shouval R, Versluis J, Bug G, Fløisand Y, Ciceri F, Sanz J, Bazarbachi A, Nagler A, Mohty M. Spyridonidis A, et al. Bone Marrow Transplant. 2020 Jun;55(6):1213. doi: 10.1038/s41409-020-0835-3. Bone Marrow Transplant. 2020. PMID: 32144364
Hematopoietic cell proliferation and differentiation.
Spyridonidis A, Mertelsmann R, Henschler R. Spyridonidis A, et al. Curr Opin Hematol. 1996 Jul;3(4):321-8. doi: 10.1097/00062752-199603040-00012. Curr Opin Hematol. 1996. PMID: 9372095 Review.
Purging of mammary carcinoma cells during ex vivo culture of CD34+ hematopoietic progenitor cells with recombinant immunotoxins.
Spyridonidis A, Schmidt M, Bernhardt W, Papadimitriou A, Azemar M, Wels W, Groner B, Henschler R. Spyridonidis A, et al. Blood. 1998 Mar 1;91(5):1820-7. Blood. 1998. PMID: 9473251
ITs were expressed from fusion cDNAs combining a single-chain antibody fragment (scFv) directed against the Erb-B2 or epidermal growth factor (EGF) receptors with a truncated Pseudomonas exotoxin A fragment devoid of its cell-binding domain. ...In contrast, M …
ITs were expressed from fusion cDNAs combining a single-chain antibody fragment (scFv) directed against the Erb-B2 or epidermal growt …
Minimal residual disease in autologous hematopoietic harvests from breast cancer patients.
Spyridonidis A, Bernhardt W, Fetscher S, Behringer D, Mertelsmann R, Henschler R. Spyridonidis A, et al. Ann Oncol. 1998 Aug;9(8):821-6. doi: 10.1023/a:1008344708061. Ann Oncol. 1998. PMID: 9789603 Review.
Minimal residual disease (MRD) in autologous grafts has became a dynamic and intensively studied field in oncology. This review discusses the current status of MRD in breast cancer autografts and presents existing data on detection methodology, clinical relevance, biologic …
Minimal residual disease (MRD) in autologous grafts has became a dynamic and intensively studied field in oncology. This review discu …
Hematopoietic stem cell transplantation: more than just hematopoietic?
Spyridonidis A, Mertelsmann R, Finke J. Spyridonidis A, et al. J Cancer Res Clin Oncol. 2004 Mar;130(3):127-34. doi: 10.1007/s00432-003-0507-x. Epub 2004 Jan 16. J Cancer Res Clin Oncol. 2004. PMID: 14727105 Review.
A wealth of evidence has surfaced in the last three years to challenge age-old notions of stem cell compartments in mammalian adult tissues. ...
A wealth of evidence has surfaced in the last three years to challenge age-old notions of stem cell compartments in mammalian adult t
Epithelial tissue chimerism after human hematopoietic cell transplantation is a real phenomenon.
Spyridonidis A, Schmitt-Gräff A, Tomann T, Dwenger A, Follo M, Behringer D, Finke J. Spyridonidis A, et al. Am J Pathol. 2004 Apr;164(4):1147-55. doi: 10.1016/S0002-9440(10)63203-8. Am J Pathol. 2004. PMID: 15039204 Free PMC article.
Bone marrow transplantation in animals has been shown to generate epithelial populations, a phenomenon that has also recently been suggested to take place after human hematopoietic cell transplantation. ...By using a rigorous three-dimensional analysis on single sec …
Bone marrow transplantation in animals has been shown to generate epithelial populations, a phenomenon that has also recently been su …
Evidence for a graft-versus-mast-cell effect after allogeneic bone marrow transplantation.
Spyridonidis A, Thomas AK, Bertz H, Zeiser R, Schmitt-Gräff A, Lindemann A, Waller CF, Finke J. Spyridonidis A, et al. Bone Marrow Transplant. 2004 Sep;34(6):515-9. doi: 10.1038/sj.bmt.1704627. Bone Marrow Transplant. 2004. PMID: 15273711
Mast cell leukemia (MCL) is a rare form of aggressive mastocytosis with a reported median survival below 6 months. Casuistic reports suggest the effectiveness of allogeneic bone marrow transplantation (BMT) for MCL. ...The in vitro data of our study indicate for the …
Mast cell leukemia (MCL) is a rare form of aggressive mastocytosis with a reported median survival below 6 months. Casuistic r …
Donor lymphocyte infusions for multiple myeloma: clinical results and novel perspectives.
Zeiser R, Bertz H, Spyridonidis A, Houet L, Finke J. Zeiser R, et al. Bone Marrow Transplant. 2004 Dec;34(11):923-8. doi: 10.1038/sj.bmt.1704670. Bone Marrow Transplant. 2004. PMID: 15361911 Review.
Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative allogeneic hematopoietic cell transplantation.
Zeiser R, Spyridonidis A, Wäsch R, Ihorst G, Grüllich C, Bertz H, Finke J. Zeiser R, et al. Leukemia. 2005 May;19(5):814-21. doi: 10.1038/sj.leu.2403719. Leukemia. 2005. PMID: 15772700
A total of 168 individuals with acute myeloid leukemia (AML) (n = 137) and myelo dysplastic syndrome (n = 31) were investigated with CCA and LCA at mean intervals of 24 days (range: 11-116). ...Of 168 patients, 65 experienced a clinical relapse after aHCT. CCA and L
A total of 168 individuals with acute myeloid leukemia (AML) (n = 137) and myelo dysplastic syndrome (n = 31) were investigated with
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