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Penetration of toxic shock syndrome toxin-1 across porcine vaginal mucosa ex vivo: permeability characteristics, toxin distribution, and tissue damage.
Davis CC, Kremer MJ, Schlievert PM, Squier CA. Davis CC, et al. Am J Obstet Gynecol. 2003 Dec;189(6):1785-91. doi: 10.1016/s0002-9378(03)00873-1. Am J Obstet Gynecol. 2003. PMID: 14710116
Use of porcine vaginal tissue ex-vivo to model environmental effects on vaginal mucosa to toxic shock syndrome toxin-1.
Davis CC, Baccam M, Mantz MJ, Osborn TW, Hill DR, Squier CA. Davis CC, et al. Among authors: squier ca. Toxicol Appl Pharmacol. 2014 Jan 15;274(2):240-8. doi: 10.1016/j.taap.2013.11.021. Epub 2013 Dec 10. Toxicol Appl Pharmacol. 2014. PMID: 24333258
Cytolysins augment superantigen penetration of stratified mucosa.
Brosnahan AJ, Mantz MJ, Squier CA, Peterson ML, Schlievert PM. Brosnahan AJ, et al. Among authors: squier ca. J Immunol. 2009 Feb 15;182(4):2364-73. doi: 10.4049/jimmunol.0803283. J Immunol. 2009. PMID: 19201891 Free PMC article.
Novel toxic shock syndrome toxin-1 amino acids required for biological activity.
Brosnahan AJ, Schaefers MM, Amundson WH, Mantz MJ, Squier CA, Peterson ML, Schlievert PM. Brosnahan AJ, et al. Among authors: squier ca. Biochemistry. 2008 Dec 9;47(49):12995-3003. doi: 10.1021/bi801468w. Biochemistry. 2008. PMID: 19012411 Free PMC article.
The innate immune system is activated by stimulation of vaginal epithelial cells with Staphylococcus aureus and toxic shock syndrome toxin 1.
Peterson ML, Ault K, Kremer MJ, Klingelhutz AJ, Davis CC, Squier CA, Schlievert PM. Peterson ML, et al. Infect Immun. 2005 Apr;73(4):2164-74. doi: 10.1128/IAI.73.4.2164-2174.2005. Infect Immun. 2005. PMID: 15784559 Free PMC article.
Use of an Ex Vivo Porcine Mucosal Model to Study Superantigen Penetration.
Squier CA, Mantz MJ. Squier CA, et al. Methods Mol Biol. 2016;1396:133-147. doi: 10.1007/978-1-4939-3344-0_12. Methods Mol Biol. 2016. PMID: 26676044
Comparative permeability of human vaginal and buccal mucosa to water.
van der Bijl P, Thompson IO, Squier CA. van der Bijl P, et al. Eur J Oral Sci. 1997 Dec;105(6):571-5. doi: 10.1111/j.1600-0722.1997.tb00219.x. Eur J Oral Sci. 1997. PMID: 9469607
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