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PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.
Saavedra JE, Srinivasan A, Buzard GS, Davies KM, Waterhouse DJ, Inami K, Wilde TC, Citro ML, Cuellar M, Deschamps JR, Parrish D, Shami PJ, Findlay VJ, Townsend DM, Tew KD, Singh S, Jia L, Ji X, Keefer LK. Saavedra JE, et al. Among authors: srinivasan a. J Med Chem. 2006 Feb 9;49(3):1157-64. doi: 10.1021/jm050700k. J Med Chem. 2006. PMID: 16451080 Free PMC article.
Chemistry of the diazeniumdiolates. 3. Photoreactivity.
Srinivasan A, Kebede N, Saavedra JE, Nikolaitchik AV, Brady DA, Yourd E, Davies KM, Keefer LK, Toscano JP. Srinivasan A, et al. J Am Chem Soc. 2001 Jun 13;123(23):5465-72. doi: 10.1021/ja002898y. J Am Chem Soc. 2001. PMID: 11389628
HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH.
Salmon DJ, Torres de Holding CL, Thomas L, Peterson KV, Goodman GP, Saavedra JE, Srinivasan A, Davies KM, Keefer LK, Miranda KM. Salmon DJ, et al. Among authors: srinivasan a. Inorg Chem. 2011 Apr 18;50(8):3262-70. doi: 10.1021/ic101736e. Epub 2011 Mar 15. Inorg Chem. 2011. PMID: 21405089 Free PMC article.
Structure-Based Design of Anticancer Prodrug PABA/NO.
Ji X, Pal A, Kalathur R, Hu X, Gu Y, Saavedra JE, Buzard GS, Srinivasan A, Keefer LK, Singh SV. Ji X, et al. Among authors: srinivasan a. Drug Des Devel Ther. 2008;2:123-130. doi: 10.2147/dddt.s3931. Drug Des Devel Ther. 2008. PMID: 19662104 Free PMC article.
Diagnosing and staging epithelial ovarian cancer by serum glycoproteomic profiling.
Dhar C, Ramachandran P, Xu G, Pickering C, Čaval T, Wong M, Rice R, Zhou B, Srinivasan A, Aiyetan P, Chu CW, Moser K, Herzog TJ, Olawaiye AB, Jacob F, Serie D, Lindpaintner K, Schwarz F. Dhar C, et al. Among authors: srinivasan a. Br J Cancer. 2024 Apr 24. doi: 10.1038/s41416-024-02644-4. Online ahead of print. Br J Cancer. 2024. PMID: 38658783
NSABP FB-10: a phase Ib/II trial evaluating ado-trastuzumab emtansine (T-DM1) with neratinib in women with metastatic HER2-positive breast cancer.
Jacobs SA, Wang Y, Abraham J, Feng H, Montero AJ, Lipchik C, Finnigan M, Jankowitz RC, Salkeni MA, Maley SK, Puhalla SL, Piette F, Quinn K, Chang K, Nagy RJ, Allegra CJ, Vehec K, Wolmark N, Lucas PC, Srinivasan A, Pogue-Geile KL. Jacobs SA, et al. Among authors: srinivasan a. Breast Cancer Res. 2024 Apr 22;26(1):69. doi: 10.1186/s13058-024-01823-8. Breast Cancer Res. 2024. PMID: 38650031 Free PMC article. Clinical Trial.
An accurate and rapidly calibrating speech neuroprosthesis.
Card NS, Wairagkar M, Iacobacci C, Hou X, Singer-Clark T, Willett FR, Kunz EM, Fan C, Vahdati Nia M, Deo DR, Srinivasan A, Choi EY, Glasser MF, Hochberg LR, Henderson JM, Shahlaie K, Brandman DM, Stavisky SD. Card NS, et al. Among authors: srinivasan a. medRxiv [Preprint]. 2024 Apr 10:2023.12.26.23300110. doi: 10.1101/2023.12.26.23300110. medRxiv. 2024. PMID: 38645254 Free PMC article. Preprint.
1,868 results