Srivastava RAK - Search Results

1

Curcumin and quercetin synergistically inhibit cancer cell proliferation in multiple cancer cells and modulate Wnt/β-catenin signaling and apoptotic pathways in A375 cells.

Srivastava NS, Srivastava RAK. Srivastava NS, et al. Among authors: srivastava rak. Phytomedicine. 2019 Jan;52:117-128. doi: 10.1016/j.phymed.2018.09.224. Epub 2018 Sep 28. Phytomedicine. 2019. PMID: 30599890

2

A novel anti-inflammatory natural product from Sphaeranthus indicus inhibits expression of VCAM1 and ICAM1, and slows atherosclerosis progression independent of lipid changes.

Srivastava RA, Mistry S, Sharma S. Srivastava RA, et al. Nutr Metab (Lond). 2015 Jun 5;12:20. doi: 10.1186/s12986-015-0018-1. eCollection 2015. Nutr Metab (Lond). 2015. PMID: 26064179 Free PMC article.

3

A novel BET bromodomain inhibitor, RVX-208, shows reduction of atherosclerosis in hyperlipidemic ApoE deficient mice.

Jahagirdar R, Zhang H, Azhar S, Tobin J, Attwell S, Yu R, Wu J, McLure KG, Hansen HC, Wagner GS, Young PR, Srivastava RA, Wong NC, Johansson J. Jahagirdar R, et al. Atherosclerosis. 2014 Sep;236(1):91-100. doi: 10.1016/j.atherosclerosis.2014.06.008. Epub 2014 Jun 28. Atherosclerosis. 2014. PMID: 25016363

4

Life-style-induced metabolic derangement and epigenetic changes promote diabetes and oxidative stress leading to NASH and atherosclerosis severity.

Srivastava RAK. Srivastava RAK. J Diabetes Metab Disord. 2018 Nov 29;17(2):381-391. doi: 10.1007/s40200-018-0378-y. eCollection 2018 Dec. J Diabetes Metab Disord. 2018. PMID: 30918873 Free PMC article.

5

NPC1L1 and ABCG5/8 induction explain synergistic fecal cholesterol excretion in ob/ob mice co-treated with PPAR-α and LXR agonists.

Srivastava RAK, Cefalu AB, Srivastava NS, Averna M. Srivastava RAK, et al. Mol Cell Biochem. 2020 Oct;473(1-2):247-262. doi: 10.1007/s11010-020-03826-3. Epub 2020 Jul 13. Mol Cell Biochem. 2020. PMID: 32661772

6

Rapid degradation of ABCA1 protein following cAMP withdrawal and treatment with PKA inhibitor suggests ABCA1 is a short-lived protein primarily regulated at the transcriptional level.

Srivastava N, Cefalu AB, Averna M, Srivastava RAK. Srivastava N, et al. Among authors: srivastava rak. J Diabetes Metab Disord. 2020 Mar 19;19(1):363-371. doi: 10.1007/s40200-020-00517-0. eCollection 2020 Jun. J Diabetes Metab Disord. 2020. PMID: 32550187 Free PMC article.

7

Lack of Correlation of Plasma HDL With Fecal Cholesterol and Plasma Cholesterol Efflux Capacity Suggests Importance of HDL Functionality in Attenuation of Atherosclerosis.

Srivastava N, Cefalu AB, Averna M, Srivastava RAK. Srivastava N, et al. Among authors: srivastava rak. Front Physiol. 2018 Sep 11;9:1222. doi: 10.3389/fphys.2018.01222. eCollection 2018. Front Physiol. 2018. PMID: 30271349 Free PMC article.

8

Gemcabene, a First-in-Class Hypolipidemic Small Molecule in Clinical Development, Attenuates Osteoarthritis and Pain in Animal Models of Arthritis and Pain.

Srivastava RAK, Cornicelli JA, Markham B, Bisgaier CL. Srivastava RAK, et al. Front Pharmacol. 2018 May 11;9:471. doi: 10.3389/fphar.2018.00471. eCollection 2018. Front Pharmacol. 2018. PMID: 29867478 Free PMC article.

9

Gemcabene, a first-in-class lipid-lowering agent in late-stage development, down-regulates acute-phase C-reactive protein via C/EBP-δ-mediated transcriptional mechanism.

Srivastava RAK, Cornicelli JA, Markham B, Bisgaier CL. Srivastava RAK, et al. Mol Cell Biochem. 2018 Dec;449(1-2):167-183. doi: 10.1007/s11010-018-3353-5. Epub 2018 Apr 11. Mol Cell Biochem. 2018. PMID: 29644527 Free PMC article.

10

Comparative Evaluation of Gemcabene and Peroxisome Proliferator-Activated Receptor Ligands in Transcriptional Assays of Peroxisome Proliferator-Activated Receptors: Implication for the Treatment of Hyperlipidemia and Cardiovascular Disease.

Bisgaier CL, Oniciu DC, Srivastava RAK. Bisgaier CL, et al. Among authors: srivastava rak. J Cardiovasc Pharmacol. 2018 Jul;72(1):3-10. doi: 10.1097/FJC.0000000000000580. J Cardiovasc Pharmacol. 2018. PMID: 29621036 Free PMC article.

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