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Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.
Sun L, Chen Y, Rajendran C, Mueller U, Panjikar S, Wang M, Mindnich R, Rosenthal C, Penning TM, Stöckigt J. Sun L, et al. Among authors: stockigt j. J Biol Chem. 2012 Mar 30;287(14):11213-21. doi: 10.1074/jbc.M111.335521. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334702 Free PMC article.
Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants.
Rosenthal C, Mueller U, Panjikar S, Sun L, Ruppert M, Zhao Y, Stöckigt J. Rosenthal C, et al. Among authors: stockigt j. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1286-9. doi: 10.1107/S174430910605041X. Epub 2006 Nov 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17142919 Free PMC article.
Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours.
Xia L, Lin H, Staniek A, Panjikar S, Ruppert M, Hilgers P, Williardt J, Rajendran C, Wang M, Warzecha H, Jäger V, Stöckigt J. Xia L, et al. Among authors: stockigt j. J Enzyme Inhib Med Chem. 2015 Jun;30(3):472-8. doi: 10.3109/14756366.2014.949252. Epub 2014 Aug 20. J Enzyme Inhib Med Chem. 2015. PMID: 25140865
Using Strictosidine Synthase to Prepare Novel Alkaloids.
Zhu H, Kerčmar P, Wu F, Rajendran C, Sun L, Wang M, Stöckigt J. Zhu H, et al. Among authors: stockigt j. Curr Med Chem. 2015 Apr 8. Online ahead of print. Curr Med Chem. 2015. PMID: 25850764
234 results