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Short peptides self-assemble to produce catalytic amyloids.
Rufo CM, Moroz YS, Moroz OV, Stöhr J, Smith TA, Hu X, DeGrado WF, Korendovych IV. Rufo CM, et al. Among authors: stohr j. Nat Chem. 2014 Apr;6(4):303-9. doi: 10.1038/nchem.1894. Epub 2014 Mar 16. Nat Chem. 2014. PMID: 24651196 Free PMC article.
Zinc-binding structure of a catalytic amyloid from solid-state NMR.
Lee M, Wang T, Makhlynets OV, Wu Y, Polizzi NF, Wu H, Gosavi PM, Stöhr J, Korendovych IV, DeGrado WF, Hong M. Lee M, et al. Among authors: stohr j. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6191-6196. doi: 10.1073/pnas.1706179114. Epub 2017 May 31. Proc Natl Acad Sci U S A. 2017. PMID: 28566494 Free PMC article.
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
Stöhr J, Wu H, Nick M, Wu Y, Bhate M, Condello C, Johnson N, Rodgers J, Lemmin T, Acharya S, Becker J, Robinson K, Kelly MJS, Gai F, Stubbs G, Prusiner SB, DeGrado WF. Stöhr J, et al. Nat Chem. 2017 Sep;9(9):874-881. doi: 10.1038/nchem.2754. Epub 2017 Apr 3. Nat Chem. 2017. PMID: 28837163 Free PMC article.
A long-lived Aβ oligomer resistant to fibrillization.
Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF. Nick M, et al. Among authors: stohr j. Biopolymers. 2018 Aug;109(8):e23096. doi: 10.1002/bip.23096. Epub 2018 Jan 10. Biopolymers. 2018. PMID: 29319162 Free PMC article.
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.
Condello C, Lemmin T, Stöhr J, Nick M, Wu Y, Maxwell AM, Watts JC, Caro CD, Oehler A, Keene CD, Bird TD, van Duinen SG, Lannfelt L, Ingelsson M, Graff C, Giles K, DeGrado WF, Prusiner SB. Condello C, et al. Among authors: stohr j. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E782-E791. doi: 10.1073/pnas.1714966115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311311 Free PMC article.
Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain.
Aoyagi A, Condello C, Stöhr J, Yue W, Rivera BM, Lee JC, Woerman AL, Halliday G, van Duinen S, Ingelsson M, Lannfelt L, Graff C, Bird TD, Keene CD, Seeley WW, DeGrado WF, Prusiner SB. Aoyagi A, et al. Among authors: stohr j. Sci Transl Med. 2019 May 1;11(490):eaat8462. doi: 10.1126/scitranslmed.aat8462. Sci Transl Med. 2019. PMID: 31043574 Free PMC article.
Structural studies of truncated forms of the prion protein PrP.
Wan W, Wille H, Stöhr J, Kendall A, Bian W, McDonald M, Tiggelaar S, Watts JC, Prusiner SB, Stubbs G. Wan W, et al. Among authors: stohr j. Biophys J. 2015 Mar 24;108(6):1548-1554. doi: 10.1016/j.bpj.2015.01.008. Biophys J. 2015. PMID: 25809267 Free PMC article.
158 results