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Inflammatory mediators and islet beta-cell failure: a link between type 1 and type 2 diabetes.
Donath MY, Størling J, Maedler K, Mandrup-Poulsen T. Donath MY, et al. Among authors: storling j. J Mol Med (Berl). 2003 Aug;81(8):455-70. doi: 10.1007/s00109-003-0450-y. Epub 2003 Jul 18. J Mol Med (Berl). 2003. PMID: 12879149 Review.
Calcium- and proteasome-dependent degradation of the JNK scaffold protein islet-brain 1.
Allaman-Pillet N, Størling J, Oberson A, Roduit R, Negri S, Sauser C, Nicod P, Beckmann JS, Schorderet DF, Mandrup-Poulsen T, Bonny C. Allaman-Pillet N, et al. Among authors: storling j. J Biol Chem. 2003 Dec 5;278(49):48720-6. doi: 10.1074/jbc.M306745200. Epub 2003 Sep 24. J Biol Chem. 2003. PMID: 14507925
Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
Maedler K, Størling J, Sturis J, Zuellig RA, Spinas GA, Arkhammar PO, Mandrup-Poulsen T, Donath MY. Maedler K, et al. Among authors: storling j. Diabetes. 2004 Jul;53(7):1706-13. doi: 10.2337/diabetes.53.7.1706. Diabetes. 2004. PMID: 15220194
Type 1 database mellitus: an inflammatory disease of the islet.
Bergholdt R, Heding P, Nielsen K, Nolsøe R, Sparre T, Størling J, Nerup J, Pociot F, Mandrup-Poulsen T. Bergholdt R, et al. Among authors: storling j. Adv Exp Med Biol. 2004;552:129-53. Adv Exp Med Biol. 2004. PMID: 15622962 Review. No abstract available.
Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3.
Karlsen AE, Størling ZM, Sparre T, Larsen MR, Mahmood A, Størling J, Roepstorff P, Wrzesinski K, Larsen PM, Fey S, Nielsen K, Heding P, Ricordi C, Johannesen J, Kristiansen OP, Christensen UB, Kockum I, Luthman H, Nerup J, Pociot F. Karlsen AE, et al. Among authors: storling zm, storling j. Biochem Biophys Res Commun. 2006 May 26;344(1):406-15. doi: 10.1016/j.bbrc.2006.03.105. Epub 2006 Mar 29. Biochem Biophys Res Commun. 2006. PMID: 16600178
RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.
Zaitseva II, Sharoyko V, Størling J, Efendic S, Guerin C, Mandrup-Poulsen T, Nicotera P, Berggren PO, Zaitsev SV. Zaitseva II, et al. Among authors: storling j. Biochem Biophys Res Commun. 2006 Sep 8;347(4):1121-8. doi: 10.1016/j.bbrc.2006.06.197. Epub 2006 Jul 14. Biochem Biophys Res Commun. 2006. PMID: 16870144
The Fas pathway is involved in pancreatic beta cell secretory function.
Schumann DM, Maedler K, Franklin I, Konrad D, Størling J, Böni-Schnetzler M, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, Halban PA, Mandrup-Poulsen T, Wollheim CB, Donath MY. Schumann DM, et al. Among authors: storling j. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2861-6. doi: 10.1073/pnas.0611487104. Epub 2007 Feb 13. Proc Natl Acad Sci U S A. 2007. PMID: 17299038 Free PMC article.
Cytokines and beta-cell biology: from concept to clinical translation.
Donath MY, Størling J, Berchtold LA, Billestrup N, Mandrup-Poulsen T. Donath MY, et al. Among authors: storling j. Endocr Rev. 2008 May;29(3):334-50. doi: 10.1210/er.2007-0033. Epub 2007 Nov 29. Endocr Rev. 2008. PMID: 18048762 Review.
Interleukin-1 beta targeted therapy for type 2 diabetes.
Maedler K, Dharmadhikari G, Schumann DM, Størling J. Maedler K, et al. Among authors: storling j. Expert Opin Biol Ther. 2009 Sep;9(9):1177-88. doi: 10.1517/14712590903136688. Expert Opin Biol Ther. 2009. PMID: 19604125 Review.
Candidate genes expressed in human islets and their role in the pathogenesis of type 1 diabetes.
Storling J, Brorsson CA. Storling J, et al. Curr Diab Rep. 2013 Oct;13(5):633-41. doi: 10.1007/s11892-013-0408-6. Curr Diab Rep. 2013. PMID: 23925433 Review.
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