St-Cyr DJ - Search Results

1

Targeting the INCENP IN-box-Aurora B interaction to inhibit CPC activity in vivo.

Gohard FH, St-Cyr DJ, Tyers M, Earnshaw WC. Gohard FH, et al. Among authors: st cyr dj. Open Biol. 2014 Nov;4(11):140163. doi: 10.1098/rsob.140163. Open Biol. 2014. PMID: 25392451 Free PMC article.

2

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.

Huang H, Ceccarelli DF, Orlicky S, St-Cyr DJ, Ziemba A, Garg P, Plamondon S, Auer M, Sidhu S, Marinier A, Kleiger G, Tyers M, Sicheri F. Huang H, et al. Among authors: st cyr dj. Nat Chem Biol. 2014 Feb;10(2):156-163. doi: 10.1038/nchembio.1412. Epub 2013 Dec 15. Nat Chem Biol. 2014. PMID: 24316736 Free PMC article.

3

Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing.

Castonguay E, White SA, Kagansky A, St-Cyr DJ, Castillo AG, Brugger C, White R, Bonilla C, Spitzer M, Earnshaw WC, Schalch T, Ekwall K, Tyers M, Allshire RC. Castonguay E, et al. Among authors: st cyr dj. Mol Cell Biol. 2015 Feb;35(4):662-74. doi: 10.1128/MCB.01102-14. Epub 2014 Dec 8. Mol Cell Biol. 2015. PMID: 25487573 Free PMC article.

4

Identification and optimization of molecular glue compounds that inhibit a noncovalent E2 enzyme-ubiquitin complex.

St-Cyr D, Ceccarelli DF, Orlicky S, van der Sloot AM, Tang X, Kelso S, Moore S, James C, Posternak G, Coulombe-Huntington J, Bertomeu T, Marinier A, Sicheri F, Tyers M. St-Cyr D, et al. Sci Adv. 2021 Oct 29;7(44):eabi5797. doi: 10.1126/sciadv.abi5797. Epub 2021 Oct 27. Sci Adv. 2021. PMID: 34705497 Free PMC article.

5

Head-to-tail cyclization of side chain-protected linear peptides to recapitulate genetically-encoded cyclized peptides.

Bouayad-Gervais S, St-Cyr DJ, Courcelles M, Bonneil É, Gohard FH, Thibault P, Earnshaw WC, Tyers M. Bouayad-Gervais S, et al. Among authors: st cyr dj. Pept Sci (Hoboken). 2022 May;114(3):e24254. doi: 10.1002/pep2.24254. Epub 2022 Jan 6. Pept Sci (Hoboken). 2022. PMID: 35864841 Free PMC article.

6

Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.

Chana CK, Maisonneuve P, Posternak G, Grinberg NGA, Poirson J, Ona SM, Ceccarelli DF, Mader P, St-Cyr DJ, Pau V, Kurinov I, Tang X, Deng D, Cui W, Su W, Kuai L, Soll R, Tyers M, Röst HL, Batey RA, Taipale M, Gingras AC, Sicheri F. Chana CK, et al. Among authors: st cyr dj. J Med Chem. 2022 Oct 13;65(19):12725-12746. doi: 10.1021/acs.jmedchem.2c00509. Epub 2022 Sep 18. J Med Chem. 2022. PMID: 36117290 Free PMC article.

7

A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay.

Alexander-Howden B, Zhang L, van der Sloot AM, Tollis S, St-Cyr DJ, Sicheri F, Bird AP, Tyers M, Lyst MJ. Alexander-Howden B, et al. Among authors: st cyr dj. Sci Rep. 2023 Mar 8;13(1):3868. doi: 10.1038/s41598-023-29915-z. Sci Rep. 2023. PMID: 36890145 Free PMC article.

8

A new use of Wittig-type reagents as 1,3-dipolar cycloaddition precursors and in pyrrole synthesis.

St Cyr DJ, Arndtsen BA. St Cyr DJ, et al. J Am Chem Soc. 2007 Oct 17;129(41):12366-7. doi: 10.1021/ja074330w. Epub 2007 Sep 20. J Am Chem Soc. 2007. PMID: 17880218 No abstract available.

9

Cyclic 1,3-dipoles or acyclic phosphonium ylides? Electronic characterization of "Montréalones".

Krenske EH, Houk KN, Arndtsen BA, St Cyr DJ. Krenske EH, et al. J Am Chem Soc. 2008 Aug 6;130(31):10052-3. doi: 10.1021/ja802646f. Epub 2008 Jul 11. J Am Chem Soc. 2008. PMID: 18616248

10

alpha-Amino-beta-hydroxy-gamma-lactam for constraining peptide Ser and Thr residue conformation.

St-Cyr DJ, Jamieson AG, Lubell WD. St-Cyr DJ, et al. Org Lett. 2010 Apr 16;12(8):1652-5. doi: 10.1021/ol1000582. Org Lett. 2010. PMID: 20225885

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