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Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.
Charton J, Deprez-Poulain R, Hennuyer N, Tailleux A, Staels B, Deprez B. Charton J, et al. Among authors: staels b. Bioorg Med Chem Lett. 2009 Jan 15;19(2):489-92. doi: 10.1016/j.bmcl.2008.11.040. Epub 2008 Nov 18. Bioorg Med Chem Lett. 2009. PMID: 19058965 Free article.
The orphan nuclear receptor Rev-Erbalpha is a peroxisome proliferator-activated receptor (PPAR) gamma target gene and promotes PPARgamma-induced adipocyte differentiation.
Fontaine C, Dubois G, Duguay Y, Helledie T, Vu-Dac N, Gervois P, Soncin F, Mandrup S, Fruchart JC, Fruchart-Najib J, Staels B. Fontaine C, et al. Among authors: staels b. J Biol Chem. 2003 Sep 26;278(39):37672-80. doi: 10.1074/jbc.M304664200. Epub 2003 Jun 23. J Biol Chem. 2003. PMID: 12821652 Free article.
Studies towards the conception of new selective PPARbeta/delta ligands.
Basséne CE, Suzenet F, Hennuyer N, Staels B, Caignard DH, Dacquet C, Renard P, Guillaumet G. Basséne CE, et al. Among authors: staels b. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4528-32. doi: 10.1016/j.bmcl.2006.06.028. Epub 2006 Jun 23. Bioorg Med Chem Lett. 2006. PMID: 16797985
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARgamma agonists.
Blanc-Delmas E, Lebegue N, Wallez V, Leclerc V, Yous S, Carato P, Farce A, Bennejean C, Renard P, Caignard DH, Audinot-Bouchez V, Chomarat P, Boutin J, Hennuyer N, Louche K, Carmona MC, Staels B, Pénicaud L, Casteilla L, Lonchampt M, Dacquet C, Chavatte P, Berthelot P, Lesieur D. Blanc-Delmas E, et al. Among authors: staels b. Bioorg Med Chem. 2006 Nov 15;14(22):7377-91. doi: 10.1016/j.bmc.2006.07.029. Epub 2006 Aug 2. Bioorg Med Chem. 2006. PMID: 16887353
760 results