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41 results
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DNA sequence-enabled reassembly of the green fluorescent protein.
Stains CI, Porter JR, Ooi AT, Segal DJ, Ghosh I. Stains CI, et al. J Am Chem Soc. 2005 Aug 10;127(31):10782-3. doi: 10.1021/ja051969w. J Am Chem Soc. 2005. PMID: 16076155
Supramolecular Assembly of an Evolved Miniprotein Host and Fluorogenic Guest Pair.
Xu B, Zhou X, Stains CI. Xu B, et al. Among authors: stains ci. J Am Chem Soc. 2015 Nov 18;137(45):14252-5. doi: 10.1021/jacs.5b09494. Epub 2015 Nov 6. J Am Chem Soc. 2015. PMID: 26523606
A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.
Stains CI, Furman JL, Porter JR, Rajagopal S, Li Y, Wyatt RT, Ghosh I. Stains CI, et al. ACS Chem Biol. 2010 Oct 15;5(10):943-52. doi: 10.1021/cb100143m. ACS Chem Biol. 2010. PMID: 20681584 Free PMC article.
Toward a general approach for RNA-templated hierarchical assembly of split-proteins.
Furman JL, Badran AH, Ajulo O, Porter JR, Stains CI, Segal DJ, Ghosh I. Furman JL, et al. Among authors: stains ci. J Am Chem Soc. 2010 Aug 25;132(33):11692-701. doi: 10.1021/ja104395b. J Am Chem Soc. 2010. PMID: 20681585 Free PMC article.
A turn-on split-luciferase sensor for the direct detection of poly(ADP-ribose) as a marker for DNA repair and cell death.
Furman JL, Mok PW, Shen S, Stains CI, Ghosh I. Furman JL, et al. Among authors: stains ci. Chem Commun (Camb). 2011 Jan 7;47(1):397-9. doi: 10.1039/c0cc02229b. Epub 2010 Sep 9. Chem Commun (Camb). 2011. PMID: 20830433
Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA.
Furman JL, Badran AH, Shen S, Stains CI, Hannallah J, Segal DJ, Ghosh I. Furman JL, et al. Among authors: stains ci. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3748-51. doi: 10.1016/j.bmcl.2009.04.141. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457665 Free PMC article.
A general and rapid cell-free approach for the interrogation of protein-protein, protein-DNA, and protein-RNA interactions and their antagonists utilizing split-protein reporters.
Porter JR, Stains CI, Jester BW, Ghosh I. Porter JR, et al. Among authors: stains ci. J Am Chem Soc. 2008 May 21;130(20):6488-97. doi: 10.1021/ja7114579. Epub 2008 Apr 29. J Am Chem Soc. 2008. PMID: 18444624
When conjugated polymers meet amyloid fibrils.
Stains CI, Ghosh I. Stains CI, et al. ACS Chem Biol. 2007 Aug 17;2(8):525-8. doi: 10.1021/cb700165v. ACS Chem Biol. 2007. PMID: 17708668
Split beta-lactamase sensor for the sequence-specific detection of DNA methylation.
Porter JR, Stains CI, Segal DJ, Ghosh I. Porter JR, et al. Among authors: stains ci. Anal Chem. 2007 Sep 1;79(17):6702-8. doi: 10.1021/ac071163+. Epub 2007 Aug 8. Anal Chem. 2007. PMID: 17685552
Direct detection of double-stranded DNA: Molecular methods and applications for DNA diagnostics.
Ghosh I, Stains CI, Ooi AT, Segal DJ. Ghosh I, et al. Among authors: stains ci. Mol Biosyst. 2006 Nov;2(11):551-60. doi: 10.1039/b611169f. Epub 2006 Sep 28. Mol Biosyst. 2006. PMID: 17216036 Review.
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