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Gene loci associated with insulin secretion in islets from non-diabetic mice.
Keller MP, Rabaglia ME, Schueler KL, Stapleton DS, Gatti DM, Vincent M, Mitok KA, Wang Z, Ishimura T, Simonett SP, Emfinger CH, Das R, Beck T, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Keller MP, et al. Among authors: stapleton ds. J Clin Invest. 2019 Jul 25;129(10):4419-4432. doi: 10.1172/JCI129143. J Clin Invest. 2019. PMID: 31343992 Free PMC article.
Combined expression trait correlations and expression quantitative trait locus mapping.
Lan H, Chen M, Flowers JB, Yandell BS, Stapleton DS, Mata CM, Mui ET, Flowers MT, Schueler KL, Manly KF, Williams RW, Kendziorski C, Attie AD. Lan H, et al. Among authors: stapleton ds. PLoS Genet. 2006 Jan;2(1):e6. doi: 10.1371/journal.pgen.0020006. Epub 2006 Jan 20. PLoS Genet. 2006. PMID: 16424919 Free PMC article.
Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice.
Zhao E, Keller MP, Rabaglia ME, Oler AT, Stapleton DS, Schueler KL, Neto EC, Moon JY, Wang P, Wang IM, Lum PY, Ivanovska I, Cleary M, Greenawalt D, Tsang J, Choi YJ, Kleinhanz R, Shang J, Zhou YP, Howard AD, Zhang BB, Kendziorski C, Thornberry NA, Yandell BS, Schadt EE, Attie AD. Zhao E, et al. Among authors: stapleton ds. Mamm Genome. 2009 Aug;20(8):476-85. doi: 10.1007/s00335-009-9217-2. Mamm Genome. 2009. PMID: 19727952 Free PMC article.
The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, Baliga NS, Smith LM, Broman KW, Yandell BS, Kendziorski C, Attie AD. Keller MP, et al. Among authors: stapleton ds. PLoS Genet. 2016 Dec 9;12(12):e1006466. doi: 10.1371/journal.pgen.1006466. eCollection 2016 Dec. PLoS Genet. 2016. PMID: 27935966 Free PMC article.
Genetic Drivers of Pancreatic Islet Function.
Keller MP, Gatti DM, Schueler KL, Rabaglia ME, Stapleton DS, Simecek P, Vincent M, Allen S, Broman AT, Bacher R, Kendziorski C, Broman KW, Yandell BS, Churchill GA, Attie AD. Keller MP, et al. Among authors: stapleton ds. Genetics. 2018 May;209(1):335-356. doi: 10.1534/genetics.118.300864. Epub 2018 Mar 22. Genetics. 2018. PMID: 29567659 Free PMC article.
Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation.
Simonett SP, Shin S, Herring JA, Bacher R, Smith LA, Dong C, Rabaglia ME, Stapleton DS, Schueler KL, Choi J, Bernstein MN, Turkewitz DR, Perez-Cervantes C, Spaeth J, Stein R, Tessem JS, Kendziorski C, Keleş S, Moskowitz IP, Keller MP, Attie AD. Simonett SP, et al. Among authors: stapleton ds. J Clin Invest. 2021 Nov 1;131(21):e144833. doi: 10.1172/JCI144833. J Clin Invest. 2021. PMID: 34491912 Free PMC article.
Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis.
Andersen RC, Schmidt JH, Rombach J, Lycas MD, Christensen NR, Lund VK, Stapleton DS, Pedersen SS, Olsen MA, Stoklund M, Noes-Holt G, Nielsen TT, Keller MP, Jansen AM, Herlo R, Pietropaolo M, Simonsen JB, Kjærulff O, Holst B, Attie AD, Gether U, Madsen KL. Andersen RC, et al. Among authors: stapleton ds. J Clin Invest. 2022 Mar 1;132(5):e144904. doi: 10.1172/JCI144904. J Clin Invest. 2022. PMID: 35077398 Free PMC article.
35 results