Identification of transcription factor binding sites from ChIP-seq data at high resolution.
Bardet AF, Steinmann J, Bafna S, Knoblich JA, Zeitlinger J, Stark A.
Bardet AF, et al. Among authors: stark a.
Bioinformatics. 2013 Nov 1;29(21):2705-13. doi: 10.1093/bioinformatics/btt470. Epub 2013 Aug 24.
Bioinformatics. 2013.
PMID: 23980024
Free PMC article.
We show that the increased resolution reached by peakzilla is highly relevant, as closely spaced Twist binding sites are strongly enriched in transcriptional enhancers, suggesting a signature to discriminate functional from abundant non-functional or neutral TF binding. .. …
We show that the increased resolution reached by peakzilla is highly relevant, as closely spaced Twist binding sites are strongly enriched i …