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SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.
Rebsamen M, Pochini L, Stasyk T, de Araújo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G. Rebsamen M, et al. Among authors: Stasyk T. Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7. Nature. 2015. PMID: 25561175 Free PMC article.
A new highly toxic protein isolated from the death cap Amanita phalloides is an L-amino acid oxidase.
Stasyk T, Lutsik-Kordovsky M, Wernstedt C, Antonyuk V, Klyuchivska O, Souchelnytskyi S, Hellman U, Stoika R. Stasyk T, et al. FEBS J. 2010 Mar;277(5):1260-9. doi: 10.1111/j.1742-4658.2010.07557.x. Epub 2010 Feb 1. FEBS J. 2010. PMID: 20121947
A new highly cytotoxic protein, toxophallin, was recently isolated from the fruit body of the death cap Amanita phalloides mushroom [Stasyk et al. (2008) Studia Biologica 2, 21-32]. ...
A new highly cytotoxic protein, toxophallin, was recently isolated from the fruit body of the death cap Amanita phalloides mushroom [Stas
Stability of the endosomal scaffold protein LAMTOR3 depends on heterodimer assembly and proteasomal degradation.
de Araújo ME, Stasyk T, Taub N, Ebner HL, Fürst B, Filipek P, Weys SR, Hess MW, Lindner H, Kremser L, Huber LA. de Araújo ME, et al. Among authors: Stasyk T. J Biol Chem. 2013 Jun 21;288(25):18228-42. doi: 10.1074/jbc.M112.349480. Epub 2013 May 7. J Biol Chem. 2013. PMID: 23653355 Free PMC article.
Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.
de Araujo MEG, Naschberger A, Fürnrohr BG, Stasyk T, Dunzendorfer-Matt T, Lechner S, Welti S, Kremser L, Shivalingaiah G, Offterdinger M, Lindner HH, Huber LA, Scheffzek K. de Araujo MEG, et al. Among authors: Stasyk T. Science. 2017 Oct 20;358(6361):377-381. doi: 10.1126/science.aao1583. Epub 2017 Sep 21. Science. 2017. PMID: 28935770
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.
Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen M, Rudashevskaya EL, Kremser L, Yordanov T, Tschaikner P, Fürnrohr BG, Lechner S, Dunzendorfer-Matt T, Scheffzek K, Bennett KL, Superti-Furga G, Lindner HH, Stasyk T, Huber LA. Filipek PA, et al. Among authors: Stasyk T. J Cell Biol. 2017 Dec 4;216(12):4199-4215. doi: 10.1083/jcb.201703061. Epub 2017 Oct 9. J Cell Biol. 2017. PMID: 28993467 Free PMC article.
Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate.
Yordanov TE, Hipolito VEB, Liebscher G, Vogel GF, Stasyk T, Herrmann C, Geley S, Teis D, Botelho RJ, Hess MW, Huber LA. Yordanov TE, et al. Among authors: Stasyk T. Traffic. 2019 Sep;20(9):674-696. doi: 10.1111/tra.12679. Traffic. 2019. PMID: 31314175 Free PMC article.
LAMTOR/Ragulator regulates lipid metabolism in macrophages and foam cell differentiation.
Lamberti G, De Smet CH, Angelova M, Kremser L, Taub N, Herrmann C, Hess MW, Rainer J, Tancevski I, Schweigreiter R, Kofler R, Schmiedinger T, Vietor I, Trajanoski Z, Ejsing CS, Lindner HH, Huber LA, Stasyk T. Lamberti G, et al. Among authors: Stasyk T. FEBS Lett. 2020 Jan;594(1):31-42. doi: 10.1002/1873-3468.13579. Epub 2019 Aug 26. FEBS Lett. 2020. PMID: 31423582 Free PMC article.
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