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High-throughput solubility assay for purified recombinant protein immunogens.
Stenvall M, Steen J, Uhlén M, Hober S, Ottosson J. Stenvall M, et al. Biochim Biophys Acta. 2005 Aug 31;1752(1):6-10. doi: 10.1016/j.bbapap.2005.07.002. Biochim Biophys Acta. 2005. PMID: 16084133
A human protein atlas for normal and cancer tissues based on antibody proteomics.
Uhlén M, Björling E, Agaton C, Szigyarto CA, Amini B, Andersen E, Andersson AC, Angelidou P, Asplund A, Asplund C, Berglund L, Bergström K, Brumer H, Cerjan D, Ekström M, Elobeid A, Eriksson C, Fagerberg L, Falk R, Fall J, Forsberg M, Björklund MG, Gumbel K, Halimi A, Hallin I, Hamsten C, Hansson M, Hedhammar M, Hercules G, Kampf C, Larsson K, Lindskog M, Lodewyckx W, Lund J, Lundeberg J, Magnusson K, Malm E, Nilsson P, Odling J, Oksvold P, Olsson I, Oster E, Ottosson J, Paavilainen L, Persson A, Rimini R, Rockberg J, Runeson M, Sivertsson A, Sköllermo A, Steen J, Stenvall M, Sterky F, Strömberg S, Sundberg M, Tegel H, Tourle S, Wahlund E, Waldén A, Wan J, Wernérus H, Westberg J, Wester K, Wrethagen U, Xu LL, Hober S, Pontén F. Uhlén M, et al. Mol Cell Proteomics. 2005 Dec;4(12):1920-32. doi: 10.1074/mcp.M500279-MCP200. Epub 2005 Aug 27. Mol Cell Proteomics. 2005. PMID: 16127175
High-throughput protein production--lessons from scaling up from 10 to 288 recombinant proteins per week.
Tegel H, Steen J, Konrad A, Nikdin H, Pettersson K, Stenvall M, Tourle S, Wrethagen U, Xu L, Yderland L, Uhlén M, Hober S, Ottosson J. Tegel H, et al. Biotechnol J. 2009 Jan;4(1):51-7. doi: 10.1002/biot.200800183. Biotechnol J. 2009. PMID: 19039781
Automated sample preparation method for mass spectrometry analysis on recombinant proteins.
Steen J, Ramström M, Uhlén M, Hober S, Ottosson J. Steen J, et al. J Chromatogr A. 2009 May 15;1216(20):4457-64. doi: 10.1016/j.chroma.2009.03.041. Epub 2009 Mar 20. J Chromatogr A. 2009. PMID: 19345368
Surrogate antigens as targets for proteome-wide binder selection.
Gustavsson E, Ek S, Steen J, Kristensson M, Älgenäs C, Uhlén M, Wingren C, Ottosson J, Hober S, Borrebaeck CA. Gustavsson E, et al. N Biotechnol. 2011 Jul;28(4):302-11. doi: 10.1016/j.nbt.2010.12.005. Epub 2011 Jan 11. N Biotechnol. 2011. PMID: 21232647
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis.
Grönwall C, Amara K, Hardt U, Krishnamurthy A, Steen J, Engström M, Sun M, Ytterberg AJ, Zubarev RA, Scheel-Toellner D, Greenberg JD, Klareskog L, Catrina AI, Malmström V, Silverman GJ. Grönwall C, et al. J Autoimmun. 2017 Nov;84:29-45. doi: 10.1016/j.jaut.2017.06.004. Epub 2017 Jun 21. J Autoimmun. 2017. PMID: 28647488
Recognition of Amino Acid Motifs, Rather Than Specific Proteins, by Human Plasma Cell-Derived Monoclonal Antibodies to Posttranslationally Modified Proteins in Rheumatoid Arthritis.
Steen J, Forsström B, Sahlström P, Odowd V, Israelsson L, Krishnamurthy A, Badreh S, Mathsson Alm L, Compson J, Ramsköld D, Ndlovu W, Rapecki S, Hansson M, Titcombe PJ, Bang H, Mueller DL, Catrina AI, Grönwall C, Skriner K, Nilsson P, Lightwood D, Klareskog L, Malmström V. Steen J, et al. Arthritis Rheumatol. 2019 Feb;71(2):196-209. doi: 10.1002/art.40699. Arthritis Rheumatol. 2019. PMID: 30152202 Free PMC article.
Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.
Amara K, Steen J, Murray F, Morbach H, Fernandez-Rodriguez BM, Joshua V, Engström M, Snir O, Israelsson L, Catrina AI, Wardemann H, Corti D, Meffre E, Klareskog L, Malmström V. Amara K, et al. J Exp Med. 2013 Mar 11;210(3):445-55. doi: 10.1084/jem.20121486. Epub 2013 Feb 25. J Exp Med. 2013. PMID: 23440041 Free PMC article. Retracted.
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