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NDR kinases regulate essential cell processes from yeast to humans.
Hergovich A, Stegert MR, Schmitz D, Hemmings BA. Hergovich A, et al. Among authors: stegert mr. Nat Rev Mol Cell Biol. 2006 Apr;7(4):253-64. doi: 10.1038/nrm1891. Nat Rev Mol Cell Biol. 2006. PMID: 16607288 Review.
Ablation of the kinase NDR1 predisposes mice to the development of T cell lymphoma.
Cornils H, Stegert MR, Hergovich A, Hynx D, Schmitz D, Dirnhofer S, Hemmings BA. Cornils H, et al. Among authors: stegert mr. Sci Signal. 2010 Jun 15;3(126):ra47. doi: 10.1126/scisignal.2000681. Sci Signal. 2010. PMID: 20551432 Free article.
Regulation of NDR protein kinase by hydrophobic motif phosphorylation mediated by the mammalian Ste20-like kinase MST3.
Stegert MR, Hergovich A, Tamaskovic R, Bichsel SJ, Hemmings BA. Stegert MR, et al. Mol Cell Biol. 2005 Dec;25(24):11019-29. doi: 10.1128/MCB.25.24.11019-11029.2005. Mol Cell Biol. 2005. PMID: 16314523 Free PMC article.
Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein.
Bichsel SJ, Tamaskovic R, Stegert MR, Hemmings BA. Bichsel SJ, et al. Among authors: stegert mr. J Biol Chem. 2004 Aug 20;279(34):35228-35. doi: 10.1074/jbc.M404542200. Epub 2004 Jun 14. J Biol Chem. 2004. PMID: 15197186 Free article.
Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase.
Tamaskovic R, Bichsel SJ, Rogniaux H, Stegert MR, Hemmings BA. Tamaskovic R, et al. Among authors: stegert mr. J Biol Chem. 2003 Feb 28;278(9):6710-8. doi: 10.1074/jbc.M210590200. Epub 2002 Dec 17. J Biol Chem. 2003. PMID: 12493777 Free article.
Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation.
Dierks C, Beigi R, Guo GR, Zirlik K, Stegert MR, Manley P, Trussell C, Schmitt-Graeff A, Landwerlin K, Veelken H, Warmuth M. Dierks C, et al. Among authors: stegert mr. Cancer Cell. 2008 Sep 9;14(3):238-49. doi: 10.1016/j.ccr.2008.08.003. Cancer Cell. 2008. PMID: 18772113 Free article.