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Relative nutritional deficiencies associated with centrally acting monoamines.
Hinz M, Stein A, Uncini T. Hinz M, et al. Among authors: stein a. Int J Gen Med. 2012;5:413-30. doi: 10.2147/IJGM.S31179. Epub 2012 May 8. Int J Gen Med. 2012. PMID: 22615537 Free PMC article.
An absolute nutritional deficiency occurs when nutrient intake is not sufficient to meet the normal needs of the system, and a relative nutritional deficiency exists when nutrient intake and systemic levels of nutrients are normal, while a change occurs in the syste …
An absolute nutritional deficiency occurs when nutrient intake is not sufficient to meet the normal needs of the system, and a relati …
Parkinson's disease managing reversible neurodegeneration.
Hinz M, Stein A, Cole T, McDougall B, Westaway M. Hinz M, et al. Among authors: stein a. Neuropsychiatr Dis Treat. 2016 Apr 5;12:763-75. doi: 10.2147/NDT.S98367. eCollection 2016. Neuropsychiatr Dis Treat. 2016. PMID: 27103805 Free PMC article.
Documented herein is a novel nutritional approach for reversible processes management which may slow or halt irreversible progressive neurodegenerative disease and correct reversible RNDs whose symptoms are identical to the patient's PD symptoms....
Documented herein is a novel nutritional approach for reversible processes management which may slow or halt irreversible progressive …
The Parkinson's disease death rate: carbidopa and vitamin B6.
Hinz M, Stein A, Cole T. Hinz M, et al. Among authors: stein a. Clin Pharmacol. 2014 Oct 21;6:161-9. doi: 10.2147/CPAA.S70707. eCollection 2014. Clin Pharmacol. 2014. PMID: 25364278 Free PMC article.
The administration of carbidopa and benserazide potentially induces a nutritional catastrophe. During the first 15 years of prescribing L-dopa, a decreasing Parkinson's disease death rate was observed. ...Carbidopa is postulated to contribute to the increasing Parki …
The administration of carbidopa and benserazide potentially induces a nutritional catastrophe. During the first 15 years of prescribi …
Parkinson's disease-associated melanin steal.
Hinz M, Stein A, Cole T. Hinz M, et al. Among authors: stein a. Neuropsychiatr Dis Treat. 2014 Dec 10;10:2331-7. doi: 10.2147/NDT.S74952. eCollection 2014. Neuropsychiatr Dis Treat. 2014. PMID: 25525362 Free PMC article.
While extensive statistical analysis has been performed by the authors since 2004, it was not until 2012 that a plausible explanation was formulated. ...This paper documents the current knowledge with regard to the management of retrograde phase 1 dopamine fluctuations and …
While extensive statistical analysis has been performed by the authors since 2004, it was not until 2012 that a plausible explanation …
Management of L-dopa overdose in the competitive inhibition state.
Hinz M, Stein A, Cole T. Hinz M, et al. Among authors: stein a. Drug Healthc Patient Saf. 2014 Jul 22;6:93-9. doi: 10.2147/DHPS.S67328. eCollection 2014. Drug Healthc Patient Saf. 2014. PMID: 25092997 Free PMC article.
The endogenous approach typically increases the daily L-dopa dosing value in a linear fashion until symptoms of Parkinson's disease are under control. ...This recognition requires a novel approach to optimization of daily L-dopa dosing values from that used in the e …
The endogenous approach typically increases the daily L-dopa dosing value in a linear fashion until symptoms of Parkinson's disease a …
Urinary neurotransmitter testing: considerations of spot baseline norepinephrine and epinephrine.
Hinz M, Stein A, Uncini T. Hinz M, et al. Among authors: stein a. Open Access J Urol. 2011 Feb 4;3:19-24. doi: 10.2147/OAJU.S16637. eCollection 2011. Open Access J Urol. 2011. PMID: 24198631 Free PMC article.
Our research indicates a need for physicians and decision-makers to understand the lack of validity of this type of spot baseline monoamine testing when using it in the decision-making process for neurotransmitter deficiency disorders. METHODS: Matched-pairs t-tests were p …
Our research indicates a need for physicians and decision-makers to understand the lack of validity of this type of spot baseline mon …
Neurotransmitter testing of the urine: a comprehensive analysis.
Hinz M, Stein A, Trachte G, Uncini T. Hinz M, et al. Among authors: stein a. Open Access J Urol. 2010 Oct 7;2:177-83. doi: 10.2147/OAJU.S13370. eCollection 2010. Open Access J Urol. 2010. PMID: 24198626 Free PMC article.
Baseline assays completed with no monoamine precursors differ from baseline assays performed on a different day in the same subject. ...Urinary assays performed while taking precursors can demonstrate a lack of correlation or unexpected correlations such as inverse …
Baseline assays completed with no monoamine precursors differ from baseline assays performed on a different day in the same subject. …
5-HTP efficacy and contraindications.
Hinz M, Stein A, Uncini T. Hinz M, et al. Among authors: stein a. Neuropsychiatr Dis Treat. 2012;8:323-8. doi: 10.2147/NDT.S33259. Epub 2012 Jul 19. Neuropsychiatr Dis Treat. 2012. PMID: 22888252 Free PMC article.
This nutrient has a large and strong following who advocate exaggerated and inaccurate claims relating to its effectiveness in the treatment of depression and a number of other serotonin-related diseases. ...
This nutrient has a large and strong following who advocate exaggerated and inaccurate claims relating to its effectiveness in the tr …
The discrediting of the monoamine hypothesis.
Hinz M, Stein A, Uncini T. Hinz M, et al. Among authors: stein a. Int J Gen Med. 2012;5:135-42. doi: 10.2147/IJGM.S27824. Epub 2012 Feb 14. Int J Gen Med. 2012. PMID: 22371656 Free PMC article.
BACKGROUND: The monoamine hypothesis has been recognized for over half a century as a reference point to understanding electrical dysfunction associated with disease states, and/or regulatory dysfunction related to synaptic, centrally acting monoamine concentrations …
BACKGROUND: The monoamine hypothesis has been recognized for over half a century as a reference point to understanding electri …
Monoamine depletion by reuptake inhibitors.
Hinz M, Stein A, Uncini T. Hinz M, et al. Among authors: stein a. Drug Healthc Patient Saf. 2011;3:69-77. doi: 10.2147/DHPS.S24798. Epub 2011 Oct 20. Drug Healthc Patient Saf. 2011. PMID: 22171164 Free PMC article.
A total of 46.5% (n = 93) achieved relief of symptoms (Hamilton-D rating score ≤ 7), 37 (39.8%) of whom experienced recurrence of depression symptoms, at which point an amino acid precursor formula was started. ...The "reuptake inhibitor monoamine depletion theory" of this
A total of 46.5% (n = 93) achieved relief of symptoms (Hamilton-D rating score ≤ 7), 37 (39.8%) of whom experienced recurrence of dep
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