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Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway.
Ishrat T, Sayeed I, Atif F, Hua F, Stein DG. Ishrat T, et al. Neuroscience. 2012 May 17;210:442-50. doi: 10.1016/j.neuroscience.2012.03.008. Epub 2012 Mar 16. Neuroscience. 2012. PMID: 22450229 Free PMC article.
Post-stroke infections exacerbate ischemic brain injury in middle-aged rats: immunomodulation and neuroprotection by progesterone.
Yousuf S, Atif F, Sayeed I, Wang J, Stein DG. Yousuf S, et al. Neuroscience. 2013 Jun 3;239:92-102. doi: 10.1016/j.neuroscience.2012.10.017. Epub 2012 Oct 16. Neuroscience. 2013. PMID: 23079632 Free PMC article.
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