Steinbrecher KA - Search Results

1

Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model.

Mann EA, Steinbrecher KA, Stroup C, Witte DP, Cohen MB, Giannella RA. Mann EA, et al. Among authors: steinbrecher ka. Int J Cancer. 2005 Sep 10;116(4):500-5. doi: 10.1002/ijc.21119. Int J Cancer. 2005. PMID: 15825168 Free article.

2

Transmembrane guanylate cyclase in intestinal pathophysiology.

Steinbrecher KA, Cohen MB. Steinbrecher KA, et al. Curr Opin Gastroenterol. 2011 Mar;27(2):139-45. doi: 10.1097/MOG.0b013e328341ead5. Curr Opin Gastroenterol. 2011. PMID: 21102322 Review.

3

Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation.

Steinbrecher KA, Wowk SA, Rudolph JA, Witte DP, Cohen MB. Steinbrecher KA, et al. Am J Pathol. 2002 Dec;161(6):2169-78. doi: 10.1016/S0002-9440(10)64494-X. Am J Pathol. 2002. PMID: 12466132 Free PMC article.

4

Colitis-associated cancer is dependent on the interplay between the hemostatic and inflammatory systems and supported by integrin alpha(M)beta(2) engagement of fibrinogen.

Steinbrecher KA, Horowitz NA, Blevins EA, Barney KA, Shaw MA, Harmel-Laws E, Finkelman FD, Flick MJ, Pinkerton MD, Talmage KE, Kombrinck KW, Witte DP, Palumbo JS. Steinbrecher KA, et al. Cancer Res. 2010 Apr 1;70(7):2634-43. doi: 10.1158/0008-5472.CAN-09-3465. Epub 2010 Mar 16. Cancer Res. 2010. PMID: 20233870 Free PMC article.

5

Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.

Han X, Mann E, Gilbert S, Guan Y, Steinbrecher KA, Montrose MH, Cohen MB. Han X, et al. Among authors: steinbrecher ka. PLoS One. 2011 Jan 31;6(1):e16139. doi: 10.1371/journal.pone.0016139. PLoS One. 2011. PMID: 21305056 Free PMC article.

6

Murine guanylate cyclase C regulates colonic injury and inflammation.

Steinbrecher KA, Harmel-Laws E, Garin-Laflam MP, Mann EA, Bezerra LD, Hogan SP, Cohen MB. Steinbrecher KA, et al. J Immunol. 2011 Jun 15;186(12):7205-14. doi: 10.4049/jimmunol.1002469. Epub 2011 May 9. J Immunol. 2011. PMID: 21555532 Free PMC article.

7

Guanylate cyclase C limits systemic dissemination of a murine enteric pathogen.

Mann EA, Harmel-Laws E, Cohen MB, Steinbrecher KA. Mann EA, et al. Among authors: steinbrecher ka. BMC Gastroenterol. 2013 Sep 2;13:135. doi: 10.1186/1471-230X-13-135. BMC Gastroenterol. 2013. PMID: 24004613 Free PMC article.

8

Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis.

Harmel-Laws E, Mann EA, Cohen MB, Steinbrecher KA. Harmel-Laws E, et al. Among authors: steinbrecher ka. PLoS One. 2013 Nov 11;8(11):e79180. doi: 10.1371/journal.pone.0079180. eCollection 2013. PLoS One. 2013. PMID: 24244444 Free PMC article.

9

Expression of guanylin is downregulated in mouse and human intestinal adenomas.

Steinbrecher KA, Tuohy TM, Heppner Goss K, Scott MC, Witte DP, Groden J, Cohen MB. Steinbrecher KA, et al. Biochem Biophys Res Commun. 2000 Jun 24;273(1):225-30. doi: 10.1006/bbrc.2000.2917. Biochem Biophys Res Commun. 2000. PMID: 10873591

10

Increases in guanylin and uroguanylin in a mouse model of osmotic diarrhea are guanylate cyclase C-independent.

Steinbrecher KA, Mann EA, Giannella RA, Cohen MB. Steinbrecher KA, et al. Gastroenterology. 2001 Nov;121(5):1191-202. doi: 10.1053/gast.2001.28680. Gastroenterology. 2001. PMID: 11677212

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