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Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.
Pflegerl P, Vesely P, Hantusch B, Schlederer M, Zenz R, Janig E, Steiner G, Meixner A, Petzelbauer P, Wolf P, Soleiman A, Egger G, Moriggl R, Kishimoto T, Wagner EF, Kenner L. Pflegerl P, et al. Among authors: steiner g. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20423-8. doi: 10.1073/pnas.0910371106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918056 Free PMC article.
Aberrant expression of the autoantigen heterogeneous nuclear ribonucleoprotein-A2 (RA33) and spontaneous formation of rheumatoid arthritis-associated anti-RA33 autoantibodies in TNF-alpha transgenic mice.
Hayer S, Tohidast-Akrad M, Haralambous S, Jahn-Schmid B, Skriner K, Trembleau S, Dumortier H, Pinol-Roma S, Redlich K, Schett G, Muller S, Kollias G, Smolen J, Steiner G. Hayer S, et al. Among authors: steiner g. J Immunol. 2005 Dec 15;175(12):8327-36. doi: 10.4049/jimmunol.175.12.8327. J Immunol. 2005. PMID: 16339574
Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation.
Görtz B, Hayer S, Redlich K, Zwerina J, Tohidast-Akrad M, Tuerk B, Hartmann C, Kollias G, Steiner G, Smolen JS, Schett G. Görtz B, et al. Among authors: steiner g. J Bone Miner Res. 2004 Jun;19(6):990-8. doi: 10.1359/JBMR.040205. Epub 2004 Feb 9. J Bone Miner Res. 2004. PMID: 15125796 Free article.
IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.
Bonelli M, Dalwigk K, Platzer A, Olmos Calvo I, Hayer S, Niederreiter B, Holinka J, Sevelda F, Pap T, Steiner G, Superti-Furga G, Smolen JS, Kiener HP, Karonitsch T. Bonelli M, et al. Among authors: steiner g. Exp Mol Med. 2019 Jul 8;51(7):1-11. doi: 10.1038/s12276-019-0267-6. Exp Mol Med. 2019. PMID: 31285419 Free PMC article.
Osteoclasts are essential for TNF-alpha-mediated joint destruction.
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Redlich K, et al. Among authors: steiner g. J Clin Invest. 2002 Nov;110(10):1419-27. doi: 10.1172/JCI15582. J Clin Invest. 2002. PMID: 12438440 Free PMC article.
944 results