Steinhilber D - Search Results

1

A Dual Modulator of Farnesoid X Receptor and Soluble Epoxide Hydrolase To Counter Nonalcoholic Steatohepatitis.

Schmidt J, Rotter M, Weiser T, Wittmann S, Weizel L, Kaiser A, Heering J, Goebel T, Angioni C, Wurglics M, Paulke A, Geisslinger G, Kahnt A, Steinhilber D, Proschak E, Merk D. Schmidt J, et al. Among authors: steinhilber d. J Med Chem. 2017 Sep 28;60(18):7703-7724. doi: 10.1021/acs.jmedchem.7b00398. Epub 2017 Sep 8. J Med Chem. 2017. PMID: 28845983

2

5-Lipoxygenase: a target for antiinflammatory drugs revisited.

Steinhilber D. Steinhilber D. Curr Med Chem. 1999 Jan;6(1):71-85. Curr Med Chem. 1999. PMID: 9873115 Review.

3

Synthesis of thieno[2,3-b]pyridinones acting as cytoprotectants and as inhibitors of [3H]glycine binding to the N-methyl-D-aspartate (NMDA) receptor.

Buchstaller HP, Siebert CD, Steinmetz R, Frank I, Berger ML, Gottschlich R, Leibrock J, Krug M, Steinhilber D, Noe CR. Buchstaller HP, et al. Among authors: steinhilber d. J Med Chem. 2006 Feb 9;49(3):864-71. doi: 10.1021/jm0503493. J Med Chem. 2006. PMID: 16451052

4

Scaffold-hopping cascade yields potent inhibitors of 5-lipoxygenase.

Hofmann B, Franke L, Proschak E, Tanrikulu Y, Schneider P, Steinhilber D, Schneider G. Hofmann B, et al. Among authors: steinhilber d. ChemMedChem. 2008 Oct;3(10):1535-8. doi: 10.1002/cmdc.200800153. ChemMedChem. 2008. PMID: 18688907 No abstract available.

5

Celecoxib inhibits 5-lipoxygenase.

Maier TJ, Tausch L, Hoernig M, Coste O, Schmidt R, Angioni C, Metzner J, Groesch S, Pergola C, Steinhilber D, Werz O, Geisslinger G. Maier TJ, et al. Among authors: steinhilber d. Biochem Pharmacol. 2008 Oct 1;76(7):862-72. doi: 10.1016/j.bcp.2008.07.009. Epub 2008 Jul 19. Biochem Pharmacol. 2008. PMID: 18692027

6

PhAST: pharmacophore alignment search tool.

Hähnke V, Hofmann B, Grgat T, Proschak E, Steinhilber D, Schneider G. Hähnke V, et al. Among authors: steinhilber d. J Comput Chem. 2009 Apr 15;30(5):761-71. doi: 10.1002/jcc.21095. J Comput Chem. 2009. PMID: 18727161

7

Cellular membranes function as a storage compartment for celecoxib.

Maier TJ, Schiffmann S, Wobst I, Birod K, Angioni C, Hoffmann M, Lopez JJ, Glaubitz C, Steinhilber D, Geisslinger G, Grösch S. Maier TJ, et al. Among authors: steinhilber d. J Mol Med (Berl). 2009 Oct;87(10):981-93. doi: 10.1007/s00109-009-0506-8. Epub 2009 Jul 30. J Mol Med (Berl). 2009. PMID: 19641861

8

Toponomics analysis of drug-induced changes in arachidonic acid-dependent signaling pathways during spinal nociceptive processing.

Linke B, Pierre S, Coste O, Angioni C, Becker W, Maier TJ, Steinhilber D, Wittpoth C, Geisslinger G, Scholich K. Linke B, et al. Among authors: steinhilber d. J Proteome Res. 2009 Oct;8(10):4851-9. doi: 10.1021/pr900106v. J Proteome Res. 2009. PMID: 19697962

9

Sulindac sulfide suppresses 5-lipoxygenase at clinically relevant concentrations.

Steinbrink SD, Pergola C, Bühring U, George S, Metzner J, Fischer AS, Häfner AK, Wisniewska JM, Geisslinger G, Werz O, Steinhilber D, Maier TJ. Steinbrink SD, et al. Among authors: steinhilber d. Cell Mol Life Sci. 2010 Mar;67(5):797-806. doi: 10.1007/s00018-009-0206-0. Epub 2009 Nov 29. Cell Mol Life Sci. 2010. PMID: 20091083

10

5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity.

Fischer AS, Metzner J, Steinbrink SD, Ulrich S, Angioni C, Geisslinger G, Steinhilber D, Maier TJ. Fischer AS, et al. Among authors: steinhilber d. Br J Pharmacol. 2010 Oct;161(4):936-49. doi: 10.1111/j.1476-5381.2010.00915.x. Br J Pharmacol. 2010. PMID: 20860670 Free PMC article.

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