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Structural basis for the regulation of tubulin by vinblastine.
Gigant B, Wang C, Ravelli RB, Roussi F, Steinmetz MO, Curmi PA, Sobel A, Knossow M. Gigant B, et al. Among authors: steinmetz mo. Nature. 2005 May 26;435(7041):519-22. doi: 10.1038/nature03566. Nature. 2005. PMID: 15917812 Free article.
Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.
Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GF, Hoogenraad CC, Capitani G, Kammerer RA. Benoit RM, et al. Among authors: steinmetz mo. Nature. 2014 Jan 2;505(7481):108-11. doi: 10.1038/nature12732. Epub 2013 Nov 17. Nature. 2014. PMID: 24240280
Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.
Wang N, Bosc C, Ryul Choi S, Boulan B, Peris L, Olieric N, Bao H, Krichen F, Chen L, Andrieux A, Olieric V, Moutin MJ, Steinmetz MO, Huang H. Wang N, et al. Among authors: steinmetz mo. Nat Struct Mol Biol. 2019 Jul;26(7):571-582. doi: 10.1038/s41594-019-0241-y. Epub 2019 Jun 24. Nat Struct Mol Biol. 2019. PMID: 31235911
Structure-function relationship of CAP-Gly domains.
Weisbrich A, Honnappa S, Jaussi R, Okhrimenko O, Frey D, Jelesarov I, Akhmanova A, Steinmetz MO. Weisbrich A, et al. Among authors: steinmetz mo. Nat Struct Mol Biol. 2007 Oct;14(10):959-67. doi: 10.1038/nsmb1291. Epub 2007 Sep 9. Nat Struct Mol Biol. 2007. PMID: 17828277
EB1 interacts with outwardly curved and straight regions of the microtubule lattice.
Guesdon A, Bazile F, Buey RM, Mohan R, Monier S, García RR, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D. Guesdon A, et al. Among authors: steinmetz mo. Nat Cell Biol. 2016 Oct;18(10):1102-8. doi: 10.1038/ncb3412. Epub 2016 Sep 12. Nat Cell Biol. 2016. PMID: 27617931
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Bohnacker T, Prota AE, Beaufils F, Burke JE, Melone A, Inglis AJ, Rageot D, Sele AM, Cmiljanovic V, Cmiljanovic N, Bargsten K, Aher A, Akhmanova A, Díaz JF, Fabbro D, Zvelebil M, Williams RL, Steinmetz MO, Wymann MP. Bohnacker T, et al. Among authors: steinmetz mo. Nat Commun. 2017 Mar 9;8:14683. doi: 10.1038/ncomms14683. Nat Commun. 2017. PMID: 28276440 Free PMC article.
A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Atherton J, Jiang K, Stangier MM, Luo Y, Hua S, Houben K, van Hooff JJE, Joseph AP, Scarabelli G, Grant BJ, Roberts AJ, Topf M, Steinmetz MO, Baldus M, Moores CA, Akhmanova A. Atherton J, et al. Among authors: steinmetz mo. Nat Struct Mol Biol. 2017 Nov;24(11):931-943. doi: 10.1038/nsmb.3483. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991265 Free PMC article.
235 results