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A new strategy for the preparation of peptide-targeted radiopharmaceuticals based on an fmoc-lysine-derived single amino acid chelate (SAAC). automated solid-phase synthesis, NMR characterization, and in vitro screening of fMLF(SAAC)G and fMLF[(SAAC-Re(CO)3)+]G.
Stephenson KA, Zubieta J, Banerjee SR, Levadala MK, Taggart L, Ryan L, McFarlane N, Boreham DR, Maresca KP, Babich JW, Valliant JF. Stephenson KA, et al. Bioconjug Chem. 2004 Jan-Feb;15(1):128-36. doi: 10.1021/bc034128s. Bioconjug Chem. 2004. PMID: 14733592
A new strategy for the preparation of peptide-targeted technetium and rhenium radiopharmaceuticals. The automated solid-phase synthesis, characterization, labeling, and screening of a peptide-ligand library targeted at the formyl peptide receptor.
Stephenson KA, Banerjee SR, Sogbein OO, Levadala MK, McFarlane N, Boreham DR, Maresca KP, Babich JW, Zubieta J, Valliant JF. Stephenson KA, et al. Bioconjug Chem. 2005 Sep-Oct;16(5):1189-95. doi: 10.1021/bc0500591. Bioconjug Chem. 2005. PMID: 16173797
Bifunctional single amino acid chelates for labeling of biomolecules with the [Tc(CO)(3)](+) and [Re(CO)(3)](+) cores. Crystal and molecular structures of [ReBr(CO)(3)(H(2)NCH(2)C(5)H(4)N)], [Re(CO)(3)[(C(5)H(4)NCH(2))(2)NH]]Br, [Re(CO)(3)[(C(5)H(4)NCH(2))(2)NCH(2)CO(2)H]]Br, [Re(CO)(3)[X(Y)NCH(2)CO(2)CH(2)CH(3)]]Br (X = Y = 2-pyridylmethyl; X = 2-pyridylmethyl, Y = 2-(1-methylimidazolyl)methyl; X = Y = 2-(1-methylimidazolyl)methyl), [ReBr(CO)(3)[(C(5)H(4)NCH(2))NH(CH(2)C(4)H(3)S)]], and [Re(CO)(3)[(C(5)H(4)NCH(2))N(CH(2)C(4)H(3)S)(CH(2)CO(2))]].
Banerjee SR, Levadala MK, Lazarova N, Wei L, Valliant JF, Stephenson KA, Babich JW, Maresca KP, Zubieta J. Banerjee SR, et al. Among authors: stephenson ka. Inorg Chem. 2002 Dec 2;41(24):6417-25. doi: 10.1021/ic020476e. Inorg Chem. 2002. PMID: 12444786
76 results